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GLASS

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GPCR

Name	C-X-C chemokine receptor type 5
Species	Homo sapiens (Human)
Gene	CXCR5
Synonym	BLR-1 NLR neurolymphatic receptor Monocyte-derived receptor 15 MDR15 MDR-15 Gpcr6 CXCR5 CXCR-5 CXC-R5 CD185 Burkitt lymphoma receptor 1 [ Show all ]
Disease	Systemic lupus erythematosus
Length	372
Amino acid sequence	MNYPLTLEMDLENLEDLFWELDRLDNYNDTSLVENHLCPATEGPLMASFKAVFVPVAYSLIFLLGVIGNVLVLVILERHRQTRSSTETFLFHLAVADLLLVFILPFAVAEGSVGWVLGTFLCKTVIALHKVNFYCSSLLLACIAVDRYLAIVHAVHAYRHRRLLSIHITCGTIWLVGFLLALPEILFAKVSQGHHNNSLPRCTFSQENQAETHAWFTSRFLYHVAGFLLPMLVMGWCYVGVVHRLRQAQRRPQRQKAVRVAILVTSIFFLCWSPYHIVIFLDTLARLKAVDNTCKLNGSLPVAITMCEFLGLAHCCLNPMLYTFAGVKFRSDLSRLLTKLGCTGPASLCQLFPSWRRSSLSESENATSLTTF
UniProt	P32302
Protein Data Bank	N/A
GPCR-HGmod model	P32302
3D structure model	This predicted structure model is from GPCR-EXP P32302.
BioLiP	N/A
Therapeutic Target Database	T09528
ChEMBL	CHEMBL1075315
IUPHAR	N/A
DrugBank	N/A

Ligand

Name	SCHEMBL3309293
Molecular formula	C23H21NO4
IUPAC name	2-[(2-ethoxynaphthalene-1-carbonyl)amino]-1,3-dihydroindene-2-carboxylic acid
Molecular weight	375.424
Hydrogen bond acceptor	4
Hydrogen bond donor	2
XlogP	4.2
Synonyms	CHEMBL3714900 2-[(2-Ethoxy-naphthalene-1-carbonyl)-amino]-indan-2-carboxylic acid HRPVFPJSKUAKRD-UHFFFAOYSA-N
Inchi Key	HRPVFPJSKUAKRD-UHFFFAOYSA-N
Inchi ID	InChI=1S/C23H21NO4/c1-2-28-19-12-11-15-7-5-6-10-18(15)20(19)21(25)24-23(22(26)27)13-16-8-3-4-9-17(16)14-23/h3-12H,2,13-14H2,1H3,(H,24,25)(H,26,27)
PubChem CID	59314091
ChEMBL	CHEMBL3714900
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Experimental Data

Parameter	Value	Reference	Database source
IC50	19600.0 nM	None	ChEMBL

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