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GLASS

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Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	Putative P2Y purinoceptor 10
Species	Mus musculus (Mouse)
Gene	P2ry10
Synonym	P2RY10 P2Y10 purinergic receptor P2Y purinergic receptor P2Y, G-protein coupled 10 purinergic receptor P2Y10
Disease	N/A for non-human GPCRs
Length	328
Amino acid sequence	MGSNSTSSAESNCNATYLPFQYSLYATTYIFIFIPGLLANSAALWVLCRFISKKNKAIIFMINLSVADLAHILSLPLRIYYYINRHWPFQRALCLLCFYLKYLNMYASIFFLTCISLQRCLFLLKPFRARNWKRRYDVGISAVIWIVVGTACLPFPILRNAGLANSTDSCFADLGYKQMDAVVLVTMVVIAELAGFVIPVITIACCTWKTTVSLKHPPIAFQGISERKKALRMVFMCAAVFVICFTPYHINFIFYTMVKESIITSCPTVKSTLYFHPFSLCLASLCCLLDPILYYFMASEFRDQLSRHGSSVTRSRLMSRESGSSMVN
UniProt	Q8BFU7
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL3562168
IUPHAR	N/A
DrugBank	N/A

Ligand

Name	CHEMBL3814525
Molecular formula	C31H35ClNO11P
IUPAC name	(2S)-2-amino-3-[[(2R,3R)-2-[3-[2-[[3-(4-chlorophenoxy)phenyl]methoxy]phenyl]propanoyloxymethyl]oxan-3-yl]oxy-hydroxyphosphoryl]oxypropanoic acid
Molecular weight	664.041
Hydrogen bond acceptor	12
Hydrogen bond donor	3
XlogP	1.3
Synonyms	BDBM50177140
Inchi Key	HYGFIXKGSYLQJL-WIIGKZCBSA-N
Inchi ID	InChI=1S/C31H35ClNO11P/c32-23-11-13-24(14-12-23)43-25-7-3-5-21(17-25)18-40-27-8-2-1-6-22(27)10-15-30(34)41-20-29-28(9-4-16-39-29)44-45(37,38)42-19-26(33)31(35)36/h1-3,5-8,11-14,17,26,28-29H,4,9-10,15-16,18-20,33H2,(H,35,36)(H,37,38)/t26-,28+,29+/m0/s1
PubChem CID	127053035
ChEMBL	CHEMBL3814525
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has more than 10 hydrogen bond acceptor. This ligand is heavier than 500 daltons.

Experimental Data

Parameter	Value	Reference	Database source
EC50	<1000.0 nM	PMID27077565	ChEMBL
EC50	>1000.0 nM	PMID27077565	ChEMBL

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