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GLASS

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Go to the GPCR, ligand, or experimental data tables.
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GPCR

Name	N-formyl peptide receptor 2
Species	Homo sapiens (Human)
Gene	FPR2
Synonym	FPRH1 FPRH2 FPRL1 HM63 Lipoxin A4 receptor LXA4 receptor LXA4R FPR2A FPR2/ALX Fpr-rs2 ALX ALX/FPR2 ALXR FMLP-R-I FMLP-related receptor I FMLPX formyl peptide receptor 2 formyl peptide receptor, related sequence 2 Formyl peptide receptor-like 1 RFP [ Show all ]
Disease	N/A
Length	351
Amino acid sequence	METNFSTPLNEYEEVSYESAGYTVLRILPLVVLGVTFVLGVLGNGLVIWVAGFRMTRTVTTICYLNLALADFSFTATLPFLIVSMAMGEKWPFGWFLCKLIHIVVDINLFGSVFLIGFIALDRCICVLHPVWAQNHRTVSLAMKVIVGPWILALVLTLPVFLFLTTVTIPNGDTYCTFNFASWGGTPEERLKVAITMLTARGIIRFVIGFSLPMSIVAICYGLIAAKIHKKGMIKSSRPLRVLTAVVASFFICWFPFQLVALLGTVWLKEMLFYGKYKIIDILVNPTSSLAFFNSCLNPMLYVFVGQDFRERLIHSLPTSLERALSEDSAPTNDTAANSASPPAETELQAM
UniProt	P25090
Protein Data Bank	N/A
GPCR-HGmod model	P25090
3D structure model	This predicted structure model is from GPCR-EXP P25090.
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL4227
IUPHAR	223
DrugBank	N/A

Ligand

Name	SMR000025325
Molecular formula	C19H19N3O2S
IUPAC name	N-(2-ethoxyphenyl)-2-(1-phenylimidazol-2-yl)sulfanylacetamide
Molecular weight	353.44
Hydrogen bond acceptor	4
Hydrogen bond donor	1
XlogP	3.8
Synonyms	AC1MMO5T HMS2299E05 N-(2-ethoxyphenyl)-2-[(1-phenyl-1H-imidazol-2-yl)thio]acetamide MLS000090721 F0599-0049 N-(2-ethoxyphenyl)-2-(1-phenylimidazol-2-yl)sulfanyl-ethanamide ZINC2723006 AKOS024585909 IFLab1_002719 N-(2-ethoxyphenyl)-2-[(1-phenyl-2-imidazolyl)thio]acetamide CHEMBL1343699 MolPort-003-031-190 SR-01000123298 688335-54-8 HMS1419L13 N-(2-ethoxyphenyl)-2-(1-phenylimidazol-2-yl)sulfanylacetamide BDBM37727 MCULE-7664758161 N-o-phenetyl-2-[(1-phenylimidazol-2-yl)thio]acetamide cid_3241796 N-(2-ethoxyphenyl)-2-((1-phenyl-1H-imidazol-2-yl)thio)acetamide SR-01000123298-1 [ Show all ]
Inchi Key	CXQUZZKPYSHPMV-UHFFFAOYSA-N
Inchi ID	InChI=1S/C19H19N3O2S/c1-2-24-17-11-7-6-10-16(17)21-18(23)14-25-19-20-12-13-22(19)15-8-4-3-5-9-15/h3-13H,2,14H2,1H3,(H,21,23)
PubChem CID	3241796
ChEMBL	CHEMBL1343699
IUPHAR	N/A
BindingDB	37727
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Experimental Data

Parameter	Value	Reference	Database source
IC50	<66700.0 nM	N/A	BindingDB
Ki	<40300.0 nM	N/A	BindingDB

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