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GLASS

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Go to the GPCR, ligand, or experimental data tables.
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GPCR

Name	Lysophosphatidic acid receptor 5
Species	Homo sapiens (Human)
Gene	LPAR5
Synonym	G-protein coupled receptor 92 LPAR5 LPA5 receptor LPA-5 LPA receptor 5 G protein-coupled receptor 92 GPR92 G-protein coupled receptor 93 GPR93 [ Show all ]
Disease	N/A
Length	372
Amino acid sequence	MLANSSSTNSSVLPCPDYRPTHRLHLVVYSLVLAAGLPLNALALWVFLRALRVHSVVSVYMCNLAASDLLFTLSLPVRLSYYALHHWPFPDLLCQTTGAIFQMNMYGSCIFLMLINVDRYAAIVHPLRLRHLRRPRVARLLCLGVWALILVFAVPAARVHRPSRCRYRDLEVRLCFESFSDELWKGRLLPLVLLAEALGFLLPLAAVVYSSGRVFWTLARPDATQSQRRRKTVRLLLANLVIFLLCFVPYNSTLAVYGLLRSKLVAASVPARDRVRGVLMVMVLLAGANCVLDPLVYYFSAEGFRNTLRGLGTPHRARTSATNGTRAALAQSERSAVTTDATRPDAASQGLLRPSDSHSLSSFTQCPQDSAL
UniProt	Q9H1C0
Protein Data Bank	N/A
GPCR-HGmod model	Q9H1C0
3D structure model	This predicted structure model is from GPCR-EXP Q9H1C0.
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL5700
IUPHAR	124
DrugBank	N/A

Ligand

Name	CHEMBL3956413
Molecular formula	C31H28FNO4
IUPAC name	4-[[[4-(2-fluorophenoxy)benzoyl]-(4-phenylbutyl)amino]methyl]benzoic acid
Molecular weight	497.566
Hydrogen bond acceptor	5
Hydrogen bond donor	1
XlogP	6.7
Synonyms	US9464060, 21 ZINC584598164 BDBM251685 SCHEMBL16506652
Inchi Key	BKRGCMOFALKWJU-UHFFFAOYSA-N
Inchi ID	InChI=1S/C31H28FNO4/c32-28-11-4-5-12-29(28)37-27-19-17-25(18-20-27)30(34)33(21-7-6-10-23-8-2-1-3-9-23)22-24-13-15-26(16-14-24)31(35)36/h1-5,8-9,11-20H,6-7,10,21-22H2,(H,35,36)
PubChem CID	117903056
ChEMBL	CHEMBL3956413
IUPHAR	N/A
BindingDB	251685
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has a partition coefficient log P greater than 5.

Experimental Data

Parameter	Value	Reference	Database source
IC50	11.0 nM	, None	BindingDB,ChEMBL

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