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GLASS

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Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
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Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	Chemokine-like receptor 1
Species	Homo sapiens (Human)
Gene	CMKLR1
Synonym	tazarotene induced gene 2 receptor RVER1 resolvin E1 receptor Gpcr27 G-protein coupled receptor DEZ G-protein coupled receptor ChemR23 CMKLR1 chemokine receptor-like 1 Chemerin1 chemerin receptor 1 TIG2 receptor [ Show all ]
Disease	N/A
Length	373
Amino acid sequence	MRMEDEDYNTSISYGDEYPDYLDSIVVLEDLSPLEARVTRIFLVVVYSIVCFLGILGNGLVIIIATFKMKKTVNMVWFLNLAVADFLFNVFLPIHITYAAMDYHWVFGTAMCKISNFLLIHNMFTSVFLLTIISSDRCISVLLPVWSQNHRSVRLAYMACMVIWVLAFFLSSPSLVFRDTANLHGKISCFNNFSLSTPGSSSWPTHSQMDPVGYSRHMVVTVTRFLCGFLVPVLIITACYLTIVCKLQRNRLAKTKKPFKIIVTIIITFFLCWCPYHTLNLLELHHTAMPGSVFSLGLPLATALAIANSCMNPILYVFMGQDFKKFKVALFSRLVNALSEDTGHSSYPSHRSFTKMSSMNERTSMNERETGML
UniProt	Q99788
Protein Data Bank	N/A
GPCR-HGmod model	Q99788
3D structure model	This predicted structure model is from GPCR-EXP Q99788.
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL3540
IUPHAR	79
DrugBank	N/A

Ligand

Name	CHEMBL3986622
Molecular formula	C24H20F8N2O2
IUPAC name	N-[3,5-bis(trifluoromethyl)phenyl]-2-(2,6-dimethylphenyl)-5,5-difluoro-3-oxo-1,3a,4,6-tetrahydrocyclopenta[c]pyrrole-6a-carboxamide
Molecular weight	520.423
Hydrogen bond acceptor	10
Hydrogen bond donor	1
XlogP	5.3
Synonyms	SCHEMBL12728441
Inchi Key	DUFXQATXWTUIFT-UHFFFAOYSA-N
Inchi ID	InChI=1S/C24H20F8N2O2/c1-12-4-3-5-13(2)18(12)34-11-21(10-22(25,26)9-17(21)19(34)35)20(36)33-16-7-14(23(27,28)29)6-15(8-16)24(30,31)32/h3-8,17H,9-11H2,1-2H3,(H,33,36)
PubChem CID	88954713
ChEMBL	CHEMBL3986622
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons. This ligand has a partition coefficient log P greater than 5.

Experimental Data

Parameter	Value	Reference	Database source
IC50	30.0 nM	None	ChEMBL

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