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GLASS

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Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	Melatonin receptor type 1C
Species	Gallus gallus (Chicken)
Gene
Synonym	CKB Mel-1C-R Mel1c receptor
Disease	N/A for non-human GPCRs
Length	346
Amino acid sequence	MERPGSNGSCSGCRLEGGPAARAASGLAAVLIVTIVVDVLGNALVILSVLRNKKLRNAGNIFVVSLSVADLVVAVYPYPLILSAIFHNGWTMGNIHCQISGFLMGLSVIGSIFNITAIAINRYCYICHSLRYDKLFNLKNTCCYICLTWTLTVVAIVPNFFVGSLQYDPRIYSCTFAQTVSTSYTITVVVVHFIVPLSIVTFCYLRIWILVIQVKHRVRQDCKQKIRAADIRNFLTMFVVFVLFAVCWGPLNFIGLAVSINPSKVQPHIPEWLFVLSYFMAYFNSCLNAVIYGLLNQNFRKEYKRILLMLRTPRLLFIDVSKGGTEGLKSKPSPAVTNNNQAEIHL
UniProt	P49288
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL3196
IUPHAR	N/A
DrugBank	N/A

Ligand

Name	5-hydroxyethoxy-N-acetyltryptamine
Molecular formula	C14H18N2O3
IUPAC name	N-[2-[5-(2-hydroxyethoxy)-1H-indol-3-yl]ethyl]acetamide
Molecular weight	262.309
Hydrogen bond acceptor	3
Hydrogen bond donor	3
XlogP	0.1
Synonyms	CHEMBL126809 214416-49-6 DTXSID40445810 Acetamide, N-[2-[5-(2-hydroxyethoxy)-1H-indol-3-yl]ethyl]- N-[2-[5-(2-Hydroxyethoxy)-1H-indole-3-yl]ethyl]acetamide CTK0I9432 5-HEAT GTPL1345 SCHEMBL6257511 D08SGV N-[2-[5-(2-hydroxyethoxy)-1H-indol-3-yl]ethyl]acetamide [ Show all ]
Inchi Key	CZPLTTWZQPLXMQ-UHFFFAOYSA-N
Inchi ID	InChI=1S/C14H18N2O3/c1-10(18)15-5-4-11-9-16-14-3-2-12(8-13(11)14)19-7-6-17/h2-3,8-9,16-17H,4-7H2,1H3,(H,15,18)
PubChem CID	10849065
ChEMBL	CHEMBL126809
IUPHAR	1345
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Experimental Data

Parameter	Value	Reference	Database source
Relative affinity	492.0 -	PMID9748358	ChEMBL

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