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GLASS

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Go to the GPCR, ligand, or experimental data tables.
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GPCR

Name	G-protein coupled receptor 3
Species	Homo sapiens (Human)
Gene	GPR3
Synonym	adenylate cyclase constitutive activator G protein-coupled receptor R4 ACCA orphan receptor Gpcr21 GPCR3 GPR3 Gpcr20 [ Show all ]
Disease	N/A
Length	330
Amino acid sequence	MMWGAGSPLAWLSAGSGNVNVSSVGPAEGPTGPAAPLPSPKAWDVVLCISGTLVSCENALVVAIIVGTPAFRAPMFLLVGSLAVADLLAGLGLVLHFAAVFCIGSAEMSLVLVGVLAMAFTASIGSLLAITVDRYLSLYNALTYYSETTVTRTYVMLALVWGGALGLGLLPVLAWNCLDGLTTCGVVYPLSKNHLVVLAIAFFMVFGIMLQLYAQICRIVCRHAQQIALQRHLLPASHYVATRKGIATLAVVLGAFAACWLPFTVYCLLGDAHSPPLYTYLTLLPATYNSMINPIIYAFRNQDVQKVLWAVCCCCSSSKIPFRSRSPSDV
UniProt	P46089
Protein Data Bank	N/A
GPCR-HGmod model	P46089
3D structure model	This predicted structure model is from GPCR-EXP P46089.
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	N/A
IUPHAR	83
DrugBank	N/A

Ligand

Name	Diphenyleneiodonium chloride
Molecular formula	C12H8ClI
IUPAC name	8-iodoniatricyclo[7.4.0.02,7]trideca-1(13),2,4,6,9,11-hexaene;chloride
Molecular weight	314.55
Hydrogen bond acceptor	1
Hydrogen bond donor	0
XlogP	None
Synonyms	8$l^{3}-iodatricyclo[7.4.0.0^{2,7}]trideca-1(9),2,4,6,10,12-hexaen-8-ylium chloride CCG-221671 Dibenziodolium, chloride GTPL7802 MFCD00214165 SR-01000075494-1 1726AH 8\|E3-iodatricyclo[7.4.0.02,7]trideca-1(13),2,4,6,9,11-hexaen-8-ylium chloride CS-0020645 Diphenyleneiodonium chloride, 97+% HY-100965 NCGC00093801-01 UNII-7M9D81YZ2N BCP08692 D0N0GJ DTXSID00196932 KS-00001873 SCHEMBL159318 8??-iodatricyclo[7.4.0.0?,?]trideca-1(13),2,4,6,9,11-hexaen-8-ylium chloride CHEBI:77967 dibenzo[b,d]iodolium chloride HMS3261I15 MolPort-003-983-758 SR-01000075494-3 2,2'-biphenylyleneiodonium chloride AC1MBZ20 CTK8F9249 Diphenyleneiodonium chloride, >=98% I14-18990 NCGC00093801-02 [1,1'-Biphenyl]-2,2'-diyiodonium chloride 7M9D81YZ2N C12H8I.Cl Dibenziodolium chloride EU-0100367 LP00367 SR-01000075494 8lambda(3)-iodatricyclo[7.4.0.0(2),]trideca-1(13),2,4,6,9,11-hexaen-8-ylium chloride CHEMBL397686 HMS3266G10 MolPort-023-275-892 Tox21_500367 4673-26-1 AKOS015903219 D 2926 DPI I14-41043 NCGC00261052-01 [1,1'-Biphenyl]-2,2'-diyliodonium chloride [ Show all ]
Inchi Key	FCFZKAVCDNTYID-UHFFFAOYSA-M
Inchi ID	InChI=1S/C12H8I.ClH/c1-3-7-11-9(5-1)10-6-2-4-8-12(10)13-11;/h1-8H;1H/q+1;/p-1
PubChem CID	2733504
ChEMBL	N/A
IUPHAR	7802
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	Partition coefficient log P of this ligand is not available.

Experimental Data

Parameter	Value	Reference	Database source
EC50	1000.0 nM	PMID24633425	IUPHAR

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