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GLASS

You can:

Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	Lysophosphatidic acid receptor 2
Species	Mus musculus (Mouse)
Gene	Lpar2
Synonym	Pbx4 Lysophosphatidic acid receptor Edg-4 LPA2 receptor LPA-2 LPA receptor 2 endothelial differentiation gene 4, lysophosphatidic acid G-protein-coupled receptor 4 Edg4 pre-B-cell leukemia transcription factor 4 [ Show all ]
Disease	N/A for non-human GPCRs
Length	348
Amino acid sequence	MGQCYYNETIGFFYNNSGKELSLHWRPKDVVVVALGLTVSVLVLLTNLLVIAAIASNRRFHQPIYYLLGNLAAADLFAGMAYLFLMFHTGPPHCQALHQRLVPATGPAGHQPHGVSGHTAGIAVERHRSVMAVQLHSRLPRGRVVTLIVGVWAAALGLGLLPAHFWHCLCDLDSCSRMVPLFSRSYLAAWALSSLLVFLLMVAVYTRIFFYVRRRVERMAEHVSCHPRYRETTLSLVKTVVIILGAFVVCWTPGQVVLLLDGLDCKTCNVLAVEKYFLLLAEANSLVNAVVYSCRDAEMRRTFRRLLCCMCLRWSSHKSARYSASAQTGASTRIMLPENGRPLMDSTL
UniProt	Q9JL06
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	N/A
IUPHAR	273
DrugBank	N/A

Ligand

Name	D01PKC
Molecular formula	C22H27Cl2N5S2
IUPAC name	N-[(2S)-1-[4-[(3,4-dichlorophenyl)-dimethylidene-lambda6-sulfanyl]piperazin-1-yl]propan-2-yl]-7-methylthieno[3,2-d]pyrimidin-4-amine
Molecular weight	496.513
Hydrogen bond acceptor	6
Hydrogen bond donor	1
XlogP	7.1
Synonyms	GTPL6993 compound 15 [PMID: 18178086] N-[(2S)-1-[4-[(3,4-dichlorophenyl)-dimethylidene-$l^{6}-sulfanyl]piperazin-1-yl]propan-2-yl]-7-methylthieno[3,2-d]pyrimidin-4-amine
Inchi Key	WBVRCGUUZYPAGR-INIZCTEOSA-N
Inchi ID	InChI=1S/C22H27Cl2N5S2/c1-15-13-30-21-20(15)25-14-26-22(21)27-16(2)12-28-7-9-29(10-8-28)31(3,4)17-5-6-18(23)19(24)11-17/h5-6,11,13-14,16H,3-4,7-10,12H2,1-2H3,(H,25,26,27)/t16-/m0/s1
PubChem CID	73755255
ChEMBL	N/A
IUPHAR	6993
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has a partition coefficient log P greater than 5.

Experimental Data

Parameter	Value	Reference	Database source
IC50	17.0 nM	PMID18178086	IUPHAR

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