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Name | Melatonin receptor type 1C |
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Species | Xenopus laevis (African clawed frog) |
Gene | mtnr1c |
Synonym | Mel-1C-R Mel1c (alpha) receptor Mel1c receptor |
Disease | N/A for non-human GPCRs |
Length | 420 |
Amino acid sequence | MMEVNSTCLDCRTPGTIRTEQDAQDSASQGLTSALAVVLIFTIVVDVLGNILVILSVLRNKKLQNAGNLFVVSLSIADLVVAVYPYPVILIAIFQNGWTLGNIHCQISGFLMGLSVIGSVFNITAIAINRYCYICHSLRYDKLYNQRSTWCYLGLTWILTIIAIVPNFFVGSLQYDPRIFSCTFAQTVSSSYTITVVVVHFIVPLSVVTFCYLRIWVLVIQVKHRVRQDFKQKLTQTDLRNFLTMFVVFVLFAVCWAPLNFIGLAVAINPFHVAPKIPEWLFVLSYFMAYFNSCLNAVIYGVLNQNFRKEYKRILMSLLTPRLLFLDTSRGGTEGLKSKPSPAVTNNNQADMLGEARSLWLSRRNGAKMVIIIRPRKAQIAIIHQIFWPQSSWATCRQDTKITGEEDGCRELCKDGISQR |
UniProt | P49219 |
Protein Data Bank | N/A |
GPCR-HGmod model | N/A |
3D structure model | No available structures or models |
BioLiP | N/A |
Therapeutic Target Database | N/A |
ChEMBL | CHEMBL5495 |
IUPHAR | N/A |
DrugBank | N/A |
Name | 5-MeOT-N-propionyl |
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Molecular formula | C17H23N3O2 |
IUPAC name | N-[2-[3-(2-acetamidoethyl)-1H-indol-5-yl]ethyl]propanamide |
Molecular weight | 301.39 |
Hydrogen bond acceptor | 2 |
Hydrogen bond donor | 3 |
XlogP | 1.7 |
Synonyms | BDBM85239 |
Inchi Key | MNUNTXACESEZJT-UHFFFAOYSA-N |
Inchi ID | InChI=1S/C17H23N3O2/c1-3-17(22)19-8-6-13-4-5-16-15(10-13)14(11-20-16)7-9-18-12(2)21/h4-5,10-11,20H,3,6-9H2,1-2H3,(H,18,21)(H,19,22) |
PubChem CID | 57340030 |
ChEMBL | N/A |
IUPHAR | N/A |
BindingDB | 85239 |
DrugBank | N/A |
Structure | ![]() |
Lipinski's druglikeness | This ligand satisfies Lipinski's rule of five. |
Parameter | Value | Reference | Database source |
---|---|---|---|
Ki | 1.25 nM | PMID9840420 | BindingDB |
Ki | 1.27 nM | PMID9618903 | BindingDB |
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