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Name | D(4) dopamine receptor |
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Species | Mus musculus (Mouse) |
Gene | Drd4 |
Synonym | d(2C) dopamine receptor D4 receptor D4R Dopamine D4 receptor dopamine receptor 4 |
Disease | N/A for non-human GPCRs |
Length | 387 |
Amino acid sequence | MGNSSATEDGGLLAGRGPESLGTGAGLGGAGAAALVGGVLLIGLVLAGNSLVCVSVASERTLQTPTNYFIVSLAAADLLLAVLVLPLFVYSEVQGGVWLLSPRLCDTLMAMDVMLCTASIFNLCAISVDRFVAVTVPLRYNQQGQCQLLLIAATWLLSAAVASPVVCGLNDVPGRDPAVCCLENRDYVVYSSVCSFFLPCPLMLLLYWATFRGLRRWEAARHTKLHSRAPRRPSGPGPPVSDPTQGPFFPDCPPPLPSLRTSPSDSSRPESELSQRPCSPGCLLADAALPQPPEPSSRRRRGAKITGRERKAMRVLPVVVGAFLVCWTPFFVVHITRALCPACFVSPRLVSAVTWLGYVNSALNPIIYTIFNAEFRSVFRKTLRLRC |
UniProt | P51436 |
Protein Data Bank | N/A |
GPCR-HGmod model | N/A |
3D structure model | No available structures or models |
BioLiP | N/A |
Therapeutic Target Database | N/A |
ChEMBL | CHEMBL2574 |
IUPHAR | N/A |
DrugBank | N/A |
Name | SCHEMBL14061923 |
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Molecular formula | C20H25N3O2 |
IUPAC name | (2R)-4-[2-(2,3-dihydroindol-1-yl)ethyl]-2-(pyridin-2-yloxymethyl)morpholine |
Molecular weight | 339.439 |
Hydrogen bond acceptor | 5 |
Hydrogen bond donor | 0 |
XlogP | 2.7 |
Synonyms | BDBM186923 US9079895, 15r |
Inchi Key | DSTWBFPFQZUGGQ-GOSISDBHSA-N |
Inchi ID | InChI=1S/C20H25N3O2/c1-2-6-19-17(5-1)8-10-23(19)12-11-22-13-14-24-18(15-22)16-25-20-7-3-4-9-21-20/h1-7,9,18H,8,10-16H2/t18-/m1/s1 |
PubChem CID | 71062829 |
ChEMBL | N/A |
IUPHAR | N/A |
BindingDB | 186923 |
DrugBank | N/A |
Structure | ![]() |
Lipinski's druglikeness | This ligand satisfies Lipinski's rule of five. |
Parameter | Value | Reference | Database source |
---|---|---|---|
Ki | 814.0 nM | N/A | BindingDB |
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