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GLASS

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Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	P2Y purinoceptor 1
Species	Meleagris gallopavo (Wild turkey)
Gene	P2RY1
Synonym	6H1 orphan receptor ADP receptor P2Y1 Purinergic receptor
Disease	N/A for non-human GPCRs
Length	362
Amino acid sequence	MTEALISAALNGTQPELLAGGWAAGNASTKCSLTKTGFQFYYLPTVYILVFITGFLGNSVAIWMFVFHMRPWSGISVYMFNLALADFLYVLTLPALIFYYFNKTDWIFGDVMCKLQRFIFHVNLYGSILFLTCISVHRYTGVVHPLKSLGRLKKKNAVYVSSLVWALVVAVIAPILFYSGTGVRRNKTITCYDTTADEYLRSYFVYSMCTTVFMFCIPFIVILGCYGLIVKALIYKDLDNSPLRRKSIYLVIIVLTVFAVSYLPFHVMKTLNLRARLDFQTPQMCAFNDKVYATYQVTRGLASLNSCVDPILYFLAGDTFRRRLSRATRKSSRRSEPNVQSKSEEMTLNILTEYKQNGDTSL
UniProt	P49652
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL5720
IUPHAR	N/A
DrugBank	N/A

Ligand

Name	CHEMBL42554
Molecular formula	C11H17N5O9P2
IUPAC name	[5-(6-aminopurin-9-yl)-3-phosphonooxyoxolan-2-yl]methoxymethylphosphonic acid
Molecular weight	425.231
Hydrogen bond acceptor	13
Hydrogen bond donor	5
XlogP	-3.2
Synonyms	[5-(6-Amino-purin-9-yl)-3-phosphonooxy-tetrahydro-furan-2-ylmethoxymethyl]-phosphonic acid BDBM50076457
Inchi Key	GIIWFVBWXMGZIX-UHFFFAOYSA-N
Inchi ID	InChI=1S/C11H17N5O9P2/c12-10-9-11(14-3-13-10)16(4-15-9)8-1-6(25-27(20,21)22)7(24-8)2-23-5-26(17,18)19/h3-4,6-8H,1-2,5H2,(H2,12,13,14)(H2,17,18,19)(H2,20,21,22)
PubChem CID	44289637
ChEMBL	N/A
IUPHAR	N/A
BindingDB	50076457
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has more than 10 hydrogen bond acceptor.

Experimental Data

Parameter	Value	Reference	Database source
EC50	27700.0 nM	PMID10229631	BindingDB
IC50	19600.0 nM	PMID10229631	BindingDB

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