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GLASS

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Go to the GPCR, ligand, or experimental data tables.
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GPCR

Name	N-formyl peptide receptor 2
Species	Homo sapiens (Human)
Gene	FPR2
Synonym	FPRH1 FPRH2 FPRL1 HM63 Lipoxin A4 receptor LXA4 receptor LXA4R FPR2A FPR2/ALX Fpr-rs2 ALX ALX/FPR2 ALXR FMLP-R-I FMLP-related receptor I FMLPX formyl peptide receptor 2 formyl peptide receptor, related sequence 2 Formyl peptide receptor-like 1 RFP [ Show all ]
Disease	N/A
Length	351
Amino acid sequence	METNFSTPLNEYEEVSYESAGYTVLRILPLVVLGVTFVLGVLGNGLVIWVAGFRMTRTVTTICYLNLALADFSFTATLPFLIVSMAMGEKWPFGWFLCKLIHIVVDINLFGSVFLIGFIALDRCICVLHPVWAQNHRTVSLAMKVIVGPWILALVLTLPVFLFLTTVTIPNGDTYCTFNFASWGGTPEERLKVAITMLTARGIIRFVIGFSLPMSIVAICYGLIAAKIHKKGMIKSSRPLRVLTAVVASFFICWFPFQLVALLGTVWLKEMLFYGKYKIIDILVNPTSSLAFFNSCLNPMLYVFVGQDFRERLIHSLPTSLERALSEDSAPTNDTAANSASPPAETELQAM
UniProt	P25090
Protein Data Bank	N/A
GPCR-HGmod model	P25090
3D structure model	This predicted structure model is from GPCR-EXP P25090.
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL4227
IUPHAR	223
DrugBank	N/A

Ligand

Name	BDBM37804
Molecular formula	C23H25NO6
IUPAC name	4-(4-ethoxybenzoyl)-5-(5-methylfuran-2-yl)-1-(oxolan-2-ylmethyl)pyrrolidine-2,3-dione
Molecular weight	411.454
Hydrogen bond acceptor	6
Hydrogen bond donor	0
XlogP	2.7
Synonyms	(4Z)-4-[hydroxy(p-phenetyl)methylene]-5-(5-methyl-2-furyl)-1-(tetrahydrofurfuryl)pyrrolidine-2,3-quinone cid_5310684 (4Z)-4-[(4-ethoxyphenyl)-hydroxymethylidene]-5-(5-methyl-2-furanyl)-1-(2-oxolanylmethyl)pyrrolidine-2,3-dione (4Z)-4-[(4-ethoxyphenyl)-oxidanyl-methylidene]-5-(5-methylfuran-2-yl)-1-(oxolan-2-ylmethyl)pyrrolidine-2,3-dione
Inchi Key	DGLYSEVHWBXRGR-UHFFFAOYSA-N
Inchi ID	InChI=1S/C23H25NO6/c1-3-28-16-9-7-15(8-10-16)21(25)19-20(18-11-6-14(2)30-18)24(23(27)22(19)26)13-17-5-4-12-29-17/h6-11,17,19-20H,3-5,12-13H2,1-2H3
PubChem CID	91896342
ChEMBL	N/A
IUPHAR	N/A
BindingDB	37804
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Experimental Data

Parameter	Value	Reference	Database source
IC50	<66700.0 nM	N/A	BindingDB
Ki	<40300.0 nM	N/A	BindingDB

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