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Name | B1 bradykinin receptor |
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Species | Rattus norvegicus (Rat) |
Gene | Bdkrb1 |
Synonym | KB1 bradykinin receptor BKR1 BK-1 receptor B1R [ Show all ] |
Disease | N/A for non-human GPCRs |
Length | 337 |
Amino acid sequence | MASEVLLELQPSNRSLQAPANITSCESALEDWDLLYRVLPGFVITICFFGLLGNLLVLSFFLLPWRQWWWQQRQRQQRLTIAEIYLANLAASDLVFVLGLPFWAENIGNRFNWPFGTDLCRVVSGVIKANLFVSIFLVVAISQDRYRLLVYPMTSWGYRRRRQAQATCLLIWVAGGLLSIPTFLLRSVKVVPDLNVSACILLFPHEAWHFARMVELNVLGFLLPVTAIIFFNYHILASLRGQKEASRTRCGGPKGSKTTGLILTLVASFLVCWCPYHFFAFLDFLVQVRVIQDCSWKEITDLGLQLANFFAFVNSCLNPLIYVFAGRLLKTRVLGTL |
UniProt | P97583 |
Protein Data Bank | N/A |
GPCR-HGmod model | N/A |
3D structure model | No available structures or models |
BioLiP | N/A |
Therapeutic Target Database | N/A |
ChEMBL | CHEMBL4613 |
IUPHAR | 41 |
DrugBank | N/A |
Name | CHEMBL318524 |
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Molecular formula | C40H64N12O10 |
IUPAC name | (2S)-2-[[(2S)-1-[(2S)-2-[[2-[[1-[[2-[[(2S)-2-[[(2S)-2,6-diaminohexanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]acetyl]amino]cyclohexanecarbonyl]amino]acetyl]amino]-3-hydroxypropanoyl]pyrrolidine-2-carbonyl]amino]-3-phenylpropanoic acid |
Molecular weight | 873.026 |
Hydrogen bond acceptor | 13 |
Hydrogen bond donor | 12 |
XlogP | -5.0 |
Synonyms | N/A |
Inchi Key | DJKGJEBSFTYWEA-IIZANFQQSA-N |
Inchi ID | InChI=1S/C40H64N12O10/c41-18-8-5-13-26(42)33(56)49-27(14-9-19-45-39(43)44)34(57)46-23-32(55)51-40(16-6-2-7-17-40)38(62)47-22-31(54)48-29(24-53)36(59)52-20-10-15-30(52)35(58)50-28(37(60)61)21-25-11-3-1-4-12-25/h1,3-4,11-12,26-30,53H,2,5-10,13-24,41-42H2,(H,46,57)(H,47,62)(H,48,54)(H,49,56)(H,50,58)(H,51,55)(H,60,61)(H4,43,44,45)/t26-,27-,28-,29-,30-/m0/s1 |
PubChem CID | 10843315 |
ChEMBL | CHEMBL318524 |
IUPHAR | N/A |
BindingDB | N/A |
DrugBank | N/A |
Structure | ![]() |
Lipinski's druglikeness | This ligand has more than 5 hydrogen bond donor. This ligand has more than 10 hydrogen bond acceptor. This ligand is heavier than 500 daltons. |
Parameter | Value | Reference | Database source |
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pD2 | 5.1 - | PMID11170638 | ChEMBL |
zhanglabzhanggroup.org | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218