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GPCR

NameCannabinoid receptor 2
SpeciesMus musculus (Mouse)
GeneCnr2
SynonymPeripheral cannabinoid receptor
mCB2
CB2-R
CB2 receptor
CB2
[ Show all ]
DiseaseN/A for non-human GPCRs
Length347
Amino acid sequenceMEGCRETEVTNGSNGGLEFNPMKEYMILSSGQQIAVAVLCTLMGLLSALENMAVLYIILSSRRLRRKPSYLFISSLAGADFLASVIFACNFVIFHVFHGVDSNAIFLLKIGSVTMTFTASVGSLLLTAVDRYLCLCYPPTYKALVTRGRALVALCVMWVLSALISYLPLMGWTCCPSPCSELFPLIPNDYLLGWLLFIAILFSGIIYTYGYVLWKAHRHVATLAEHQDRQVPGIARMRLDVRLAKTLGLVLAVLLICWFPALALMGHSLVTTLSDQVKEAFAFCSMLCLVNSMVNPIIYALRSGEIRSAAQHCLIGWKKYLQGLGPEGKEEGPRSSVTETEADVKTT
UniProtP47936
Protein Data BankN/A
GPCR-HGmod modelN/A
3D structure modelNo available structures or models
BioLiPN/A
Therapeutic Target DatabaseN/A
ChEMBLCHEMBL5373
IUPHAR57
DrugBankN/A

Ligand

NameCHEMBL2172455
Molecular formulaC20H39NO4
IUPAC name[1-methoxy-3-(octanoylamino)propan-2-yl] octanoate
Molecular weight357.535
Hydrogen bond acceptor4
Hydrogen bond donor1
XlogP5.3
SynonymsBDBM50396291
Inchi KeyDRJWOCXPYWNJEP-UHFFFAOYSA-N
Inchi IDInChI=1S/C20H39NO4/c1-4-6-8-10-12-14-19(22)21-16-18(17-24-3)25-20(23)15-13-11-9-7-5-2/h18H,4-17H2,1-3H3,(H,21,22)
PubChem CID71449943
ChEMBLCHEMBL2172455
IUPHARN/A
BindingDB50396291
DrugBankN/A

Structure

SDF download

2D structure
Lipinski's druglikenessThis ligand has a partition coefficient log P greater than 5.

Experimental Data

ParameterValueReferenceDatabase source
Ki<1000.0 nMPMID22738638BindingDB,ChEMBL

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