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GLASS

You can:

Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	Cysteinyl leukotriene receptor 1
Species	Cavia porcellus (Guinea pig)
Gene	CYSLTR1
Synonym	CysLTR1 Cysteinyl leukotriene D4 receptor LTD4 receptor
Disease	N/A for non-human GPCRs
Length	340
Amino acid sequence	MDETGNPTIPPASNNTCYDSIDDFRNQVYSTLYSMISVVGFFGNGFVLYVLVKTYHEKSAFQVYMINLAVADLLCVCTLPLRVAYYVHKGIWLFGDFLCRLSTYALYVNLYCSIFFMTAMSFFRCVAIVFPVQNISLVTQKKARLVCIAIWMFVILTSSPFLMANTYKDEKNNTKCFEPPQDNQAKNYVLILHYVSLFIGFIIPFITIIVCYTMIIFTLLKSSMKKNLSSRKRAIGMIIVVTAAFLVSFMPYHIQRTIHLHFLHNKTKPCDSILRMQKSVVITLSLAASNCCFDPLLYFFSGGNFRRRLSTIRKYSLSSMTYIPKKKTSLPQKGKDICKE
UniProt	Q2NNR5
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL5645
IUPHAR	N/A
DrugBank	N/A

Ligand

Name	CHEMBL555048
Molecular formula	C38H31F2N3O3
IUPAC name	2-[2-[5-[[3-[(E)-2-(6,7-difluoroquinolin-2-yl)ethenyl]phenyl]methyl]-3,4-dihydro-1H-pyrido[4,3-b]indol-2-yl]ethoxy]benzoic acid
Molecular weight	615.681
Hydrogen bond acceptor	7
Hydrogen bond donor	1
XlogP	5.2
Synonyms	BDBM50296089 2-(2-(5-(3-(2-(6,7-difluoroquinolin-2-yl)vinyl)benzyl)-3,4-dihydro-1H-pyrido[4,3-b]indol-2(5H)-yl)ethoxy)benzoic acid
Inchi Key	DURQOFQIVXVCQC-WYMLVPIESA-N
Inchi ID	InChI=1S/C38H31F2N3O3/c39-32-21-27-13-15-28(41-34(27)22-33(32)40)14-12-25-6-5-7-26(20-25)23-43-35-10-3-1-8-29(35)31-24-42(17-16-36(31)43)18-19-46-37-11-4-2-9-30(37)38(44)45/h1-15,20-22H,16-19,23-24H2,(H,44,45)/b14-12+
PubChem CID	45268321
ChEMBL	CHEMBL555048
IUPHAR	N/A
BindingDB	50296089
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons. This ligand has a partition coefficient log P greater than 5.

Experimental Data

Parameter	Value	Reference	Database source
IC50	0.91 nM	PMID19505824	BindingDB,ChEMBL

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