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Name | P2Y purinoceptor 14 |
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Species | Homo sapiens (Human) |
Gene | P2RY14 |
Synonym | G-protein coupled receptor 105 GPR105 G protein-coupled receptor 105 P2Y purinoceptor 14 P2Y14 [ Show all ] |
Disease | N/A |
Length | 338 |
Amino acid sequence | MINSTSTQPPDESCSQNLLITQQIIPVLYCMVFIAGILLNGVSGWIFFYVPSSKSFIIYLKNIVIADFVMSLTFPFKILGDSGLGPWQLNVFVCRVSAVLFYVNMYVSIVFFGLISFDRYYKIVKPLWTSFIQSVSYSKLLSVIVWMLMLLLAVPNIILTNQSVREVTQIKCIELKSELGRKWHKASNYIFVAIFWIVFLLLIVFYTAITKKIFKSHLKSSRNSTSVKKKSSRNIFSIVFVFFVCFVPYHIARIPYTKSQTEAHYSCQSKEILRYMKEFTLLLSAANVCLDPIIYFFLCQPFREILCKKLHIPLKAQNDLDISRIKRGNTTLESTDTL |
UniProt | Q15391 |
Protein Data Bank | N/A |
GPCR-HGmod model | Q15391 |
3D structure model | This predicted structure model is from GPCR-EXP Q15391. |
BioLiP | N/A |
Therapeutic Target Database | N/A |
ChEMBL | CHEMBL4518 |
IUPHAR | 330 |
DrugBank | N/A |
Name | CHEMBL1162556 |
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Molecular formula | C13H25N3O11P2S |
IUPAC name | azane;tert-butyl [[(2R,3S,4R,5R)-3,4-dihydroxy-5-(4-oxo-2-sulfanylidenepyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl] hydrogen phosphate |
Molecular weight | 493.361 |
Hydrogen bond acceptor | 13 |
Hydrogen bond donor | 6 |
XlogP | None |
Synonyms | N/A |
Inchi Key | FBWRMJLNIURBEP-VYFIMUGFSA-N |
Inchi ID | InChI=1S/C13H22N2O11P2S.H3N/c1-13(2,3)25-28(21,22)26-27(19,20)23-6-7-9(17)10(18)11(24-7)15-5-4-8(16)14-12(15)29;/h4-5,7,9-11,17-18H,6H2,1-3H3,(H,19,20)(H,21,22)(H,14,16,29);1H3/t7-,9-,10-,11-;/m1./s1 |
PubChem CID | 44627695 |
ChEMBL | CHEMBL1162556 |
IUPHAR | N/A |
BindingDB | N/A |
DrugBank | N/A |
Structure | ![]() |
Lipinski's druglikeness | This ligand has more than 5 hydrogen bond donor. This ligand has more than 10 hydrogen bond acceptor. Partition coefficient log P of this ligand is not available. |
Parameter | Value | Reference | Database source |
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EC50 | 32.0 nM | PMID19902968 | ChEMBL |
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