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GLASS

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Go to the GPCR, ligand, or experimental data tables.
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Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	5-hydroxytryptamine receptor 2B
Species	Rattus norvegicus (Rat)
Gene	Htr2b
Synonym	stomach fundus serotonin receptor serotonin receptor 2B 5-HT-2B 5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled 5-HT2F 5-HT2B receptor 5-HT2B 5-HT-2F {ECO:0000303\|PubMed:1331748} Stomach fundus serotonin receptor {ECO:0000303\|PubMed:1505525} [ Show all ]
Disease	N/A for non-human GPCRs
Length	479
Amino acid sequence	MASSYKMSEQSTISEHILQKTCDHLILTDRSGLKAESAAEEMKQTAENQGNTVHWAALLIFAVIIPTIGGNILVILAVSLEKRLQYATNYFLMSLAVADLLVGLFVMPIALLTIMFEATWPLPLALCPAWLFLDVLFSTASIMHLCAISLDRYIAIKKPIQANQCNSRTTAFVKITVVWLISIGIAIPVPIKGIEADVVNAHNITCELTKDRFGSFMLFGSLAAFFAPLTIMIVTYFLTIHALRKKAYLVRNRPPQRLTRWTVSTVLQREDSSFSSPEKMVMLDGSHKDKILPNSTDETLMRRMSSAGKKPAQTISNEQRASKVLGIVFLFFLLMWCPFFITNVTLALCDSCNQTTLKTLLQIFVWVGYVSSGVNPLIYTLFNKTFREAFGRYITCNYQATKSVKVLRKCSSTLYFGNSMVENSKFFTKHGIRNGINPAMYQSPVRLRSSTIQSSSIILLNTFLTENDGDKVEDQVSYI
UniProt	P30994
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL323
IUPHAR	7
DrugBank	N/A

Ligand

Name	CHEMBL329133
Molecular formula	C23H28N2O2
IUPAC name	1-[(3,4-dimethoxyphenyl)methyl]-6-propyl-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole
Molecular weight	364.489
Hydrogen bond acceptor	3
Hydrogen bond donor	2
XlogP	4.8
Synonyms	N/A
Inchi Key	ALCNGWSUVIHDOX-UHFFFAOYSA-N
Inchi ID	InChI=1S/C23H28N2O2/c1-4-5-15-6-8-19-18(12-15)17-10-11-24-20(23(17)25-19)13-16-7-9-21(26-2)22(14-16)27-3/h6-9,12,14,20,24-25H,4-5,10-11,13H2,1-3H3
PubChem CID	10713831
ChEMBL	CHEMBL329133
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Experimental Data

Parameter	Value	Reference	Database source
-Log KB	8.64 -	PMID8709108	ChEMBL

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