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GLASS

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Go to the GPCR, ligand, or experimental data tables.
Go to the experimental data table for text mining information in PubMed ID column.
Go to the GPCR page and check other ligands which interact with it.
Go to the ligand page and check other GPCRs which it interacts with.
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GPCR

Name	Beta-3 adrenergic receptor
Species	Rattus norvegicus (Rat)
Gene	Adrb3
Synonym	beta3-adrenoceptor beta3-adrenergic receptor Beta-3 adrenoreceptor Beta-3 adrenoceptor ADRB beta 3-AR atypical beta-adrenoceptor adrenergic receptor Adrb-3 [ Show all ]
Disease	N/A for non-human GPCRs
Length	400
Amino acid sequence	MAPWPHKNGSLAFWSDAPTLDPSAANTSGLPGVPWAAALAGALLALATVGGNLLVITAIARTPRLQTITNVFVTSLATADLVVGLLVMPPGATLALTGHWPLGATGCELWTSVDVLCVTASIETLCALAVDRYLAVTNPLRYGTLVTKRRARAAVVLVWIVSATVSFAPIMSQWWRVGADAEAQECHSNPRCCSFASNMPYALLSSSVSFYLPLLVMLFVYARVFVVAKRQRRLLRRELGRFPPEESPRSPSRSPSPATVGTPTASDGVPSCGRRPARLLPLGEHRALRTLGLIMGIFSLCWLPFFLANVLRALVGPSLVPSGVFIALNWLGYANSAFNPLIYCRSPDFRDAFRRLLCSYGGRGPEEPRVVTFPASPVASRQNSPLNRFDGYEGERPFPT
UniProt	P26255
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL4031
IUPHAR	30
DrugBank	N/A

Ligand

Name	CHEMBL61071
Molecular formula	C26H32ClNO8
IUPAC name	2-(2-butoxyethoxycarbonyl)-5-[(2R)-2-[[(2R)-2-(3-chlorophenyl)-2-hydroxyethyl]amino]propyl]-1,3-benzodioxole-2-carboxylic acid
Molecular weight	521.991
Hydrogen bond acceptor	9
Hydrogen bond donor	3
XlogP	1.8
Synonyms	5-[(R)-2-[[(R)-beta-Hydroxy-3-chlorophenethyl]amino]propyl]-2-(2-butoxyethoxycarbonyl)-1,3-benzodioxole-2-carboxylic acid
Inchi Key	FWADDZDRRXLWET-CBBDYGADSA-N
Inchi ID	InChI=1S/C26H32ClNO8/c1-3-4-10-33-11-12-34-25(32)26(24(30)31)35-22-9-8-18(14-23(22)36-26)13-17(2)28-16-21(29)19-6-5-7-20(27)15-19/h5-9,14-15,17,21,28-29H,3-4,10-13,16H2,1-2H3,(H,30,31)/t17-,21+,26?/m1/s1
PubChem CID	44300371
ChEMBL	CHEMBL61071
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons.

Experimental Data

Parameter	Value	Reference	Database source
Response	83.0 %	PMID10450954	ChEMBL

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