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BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

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GPCR

NameGrowth hormone secretagogue receptor type 1
SpeciesRattus norvegicus (Rat)
GeneGhsr
SynonymGH-releasing peptide receptor
Ghrelin receptor
ghrelin receptor 1a
GHRP
GHS-R
[ Show all ]
DiseaseN/A for non-human GPCRs
Length364
Amino acid sequenceMWNATPSEEPEPNVTLDLDWDASPGNDSLPDELLPLFPAPLLAGVTATCVALFVVGISGNLLTMLVVSRFRELRTTTNLYLSSMAFSDLLIFLCMPLDLVRLWQYRPWNFGDLLCKLFQFVSESCTYATVLTITALSVERYFAICFPLRAKVVVTKGRVKLVILVIWAVAFCSAGPIFVLVGVEHENGTDPRDTNECRATEFAVRSGLLTVMVWVSSVFFFLPVFCLTVLYSLIGRKLWRRRGDAAVGASLRDQNHKQTVKMLAVVVFAFILCWLPFHVGRYLFSKSFEPGSLEIAQISQYCNLVSFVLFYLSAAINPILYNIMSKKYRVAVFKLLGFESFSQRKLSTLKDESSRAWTKSSINT
UniProtO08725
Protein Data BankN/A
GPCR-HGmod modelN/A
3D structure modelNo available structures or models
BioLiPN/A
Therapeutic Target DatabaseN/A
ChEMBLCHEMBL3278
IUPHAR246
DrugBankN/A

Known ligands

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Total entries: 108
Page:  / 2 

GLASS IDMoleculeFormulaMolecular weightH-bond acceptor / donorXlogPLipinski's druglikeness
76472D structureCHEMBL1081612C28H26FN3O2455.5333 / 15.0Yes
87632D structureCHEMBL13383C28H32N4O3472.5894 / 32.7Yes
109912D structureCHEMBL1076586C26H23N3O2409.4892 / 14.1Yes
149092D structureCHEMBL1079622C26H23ClN4O2458.9463 / 14.4Yes
172882D structureL-692,585C32H37N7O3567.6947 / 43.8No
172902D structureCHEMBL274665C32H37N7O3567.6947 / 43.8No
186442D structureCHEMBL441345C33H39N7O2565.7226 / 35.4No
4657702D structureCHEMBL3593814C29H29ClN4O5549.0247 / 34.5No
4659402D structureCHEMBL3586030C29H30N4O6530.5819 / 24.2No
4663962D structureCHEMBL3593633C33H36N4O4552.6756 / 24.6No
290872D structureCHEMBL427806C28H34N4O2458.6063 / 33.5Yes
300852D structureCHEMBL434609C32H38F2N4O3564.6786 / 24.4No
360432D structureCHEMBL392077C25H31N7O4S525.6288 / 21.5No
4677422D structureCHEMBL3593635C33H35ClN4O4587.1176 / 25.1No
546782D structureCHEMBL1080735C28H24F3N3O2491.5145 / 15.4No
577972D structureCHEMBL1079624C26H24N4O2424.5043 / 13.4Yes
615972D structureCHEMBL274237C31H35N7O3553.6677 / 43.4No
709542D structureCHEMBL431668C34H44N4O4572.755 / 34.0No
726852D structureCHEMBL14247C30H33N7O2523.6416 / 33.4No
775622D structureCHEMBL122939C34H46N4O4S606.8266 / 33.7No
851202D structureCHEMBL121960C30H38N4O3S534.7195 / 24.0No
903662D structureCHEMBL269447C28H34N4O2458.6063 / 33.5Yes
4744632D structureCHEMBL3593636C32H33ClN4O5589.0897 / 24.9No
960532D structureCHEMBL1082211C27H25N3O2423.5162 / 14.5Yes
985202D structureCHEMBL13930C28H34N4O3474.6054 / 33.3Yes
1071772D structureCHEMBL1088038C26H23FN4O2442.4944 / 13.5Yes
1119752D structureCHEMBL1081301C26H24N4O2424.5043 / 13.5Yes
1120732D structureCHEMBL268518C28H34N4O2458.6063 / 33.3Yes
4768462D structureCHEMBL3586031C30H30N4O6542.5928 / 23.5No
1178222D structureCHEMBL238155C23H28N6O2420.5176 / 22.0Yes
1181482D structureCHEMBL274786C26H25N7O2467.5336 / 32.5Yes
5538932D structurePralmorelinC45H55N9O6817.9928 / 92.5No
1292092D structureCHEMBL416712C29H31N7O2509.6146 / 33.9No
1323552D structureCHEMBL122420C32H40N4O3528.6974 / 24.2No
1624982D structureCHEMBL13984C28H29N7O2495.5876 / 33.1Yes
4836182D structureCHEMBL3586033C34H38N4O4566.7027 / 25.6No
1805862D structureCHEMBL13926C28H32N4O4488.5885 / 32.4Yes
1805872D structureCHEMBL275093C28H32N4O4488.5885 / 32.4Yes
1805882D structureCHEMBL13687C28H32N4O4488.5885 / 32.4Yes
1810652D structureCHEMBL330860C33H42N4O3542.7244 / 24.6No
1824112D structureCHEMBL1080907C28H27N3O2437.5432 / 14.9Yes
4855572D structureCHEMBL3586022C29H28N6O3S540.6428 / 25.2No
1851272D structureCHEMBL332414C32H39IN4O3654.5934 / 24.9No
1906712D structureCHEMBL331093C35H44N4O3568.7624 / 25.0No
4872292D structureCHEMBL3586020C30H29N5O3S539.6547 / 25.8No
2024492D structureCHEMBL1082189C26H26N4O3442.5194 / 13.7Yes
2036652D structureCHEMBL1080389C27H24FN3O2441.5063 / 14.6Yes
2054082D structureCHEMBL1080162C26H24N4O2424.5043 / 13.4Yes
2054282D structureCHEMBL13933C24H22N6O410.4815 / 23.1Yes
2139712D structureCHEMBL13891C28H34N4O3474.6054 / 42.3Yes
2161052D structureCHEMBL268516C27H27N7O2481.566 / 32.9Yes
2171542D structureCHEMBL236038C17H23N7O2357.4187 / 2-0.6Yes
2231362D structureCHEMBL125498C30H38N4O3S534.7195 / 23.9No
2294612D structureCHEMBL274599C28H34N4O2458.6063 / 33.7Yes
2347692D structureCHEMBL1088037C26H22F2N4O2460.4855 / 13.6Yes
4920822D structureCHEMBL3586028C27H28N4O6504.5439 / 23.5No
2363202D structureCHEMBL1081611C28H27N3O2437.5432 / 14.9Yes
4926492D structureCHEMBL3586029C30H34N4O5530.6258 / 24.6No
2421542D structureCHEMBL122108C34H42N4O3554.7354 / 24.6No
2423722D structureCHEMBL124831C34H42F2N4O4608.7317 / 34.2No
2426752D structureCHEMBL273682C33H31N7O2557.6586 / 34.5No
2488342D structureCHEMBL1080320C24H22N4O2S430.5264 / 13.6Yes
2488602D structureCHEMBL331303C36H47FN4O4618.7946 / 34.1No
2525782D structureCHEMBL13366C28H32N4O3472.5894 / 32.7Yes
2531522D structureCHEMBL330989C32H39FN4O3546.6875 / 24.3No
2694842D structureCHEMBL275795C28H34N4O4490.6045 / 42.2Yes
2710062D structureCHEMBL268231C28H32N4O4488.5885 / 32.4Yes
4970542D structureCHEMBL3586024C29H29N5O5527.5818 / 24.5No
5546762D structureCHEMBL3358452C22H23F6N5O487.4511 / 24.2No
2851122D structureCHEMBL332987C36H46N4O4598.7885 / 24.6No
4996582D structureCHEMBL3586027C29H25ClN4O4528.9937 / 25.5No
5001042D structureCHEMBL3593815C28H27F2N3O4507.5388 / 34.9No
3029552D structureCHEMBL276333C31H36N8O2552.6837 / 43.1No
3085622D structureCHEMBL262889C36H46N4O4598.7885 / 24.6No
3100842D structureL-692429C29H31N7O2509.6146 / 33.5No
3159302D structureCHEMBL13841C29H36N4O2472.6333 / 34.2Yes
5023012D structureCHEMBL3593634C32H34N4O5554.6477 / 24.5No
3339132D structureCHEMBL266836C28H29N7O2495.5876 / 33.4Yes
3405292D structureIbutamorenC27H36N4O5S528.6687 / 21.3No
3406332D structureCHEMBL274340C28H34N4O3474.6054 / 33.3Yes
3461802D structureCHEMBL273215C27H27N7O2481.566 / 32.9Yes
5061282D structureCHEMBL3586032C33H34N4O5566.6587 / 24.2No
5061762D structureCHEMBL3586026C28H27N5O5513.5548 / 24.0No
5061782D structureCHEMBL3586025C28H27N5O5513.5548 / 24.0No
3556732D structureCHEMBL369482C46H56N12O6873.0329 / 101.5No
5070502D structureCHEMBL3586023C30H31N5O4525.6097 / 24.7No
3586462D structureCHEMBL1082190C24H23N5O2413.4813 / 22.8Yes
3645502D structureCHEMBL13675C28H34N4O4490.6045 / 42.2Yes
3719762D structureCHEMBL1080938C26H24N4O2424.5043 / 13.5Yes
3828412D structureTabimorelinC32H40N4O3528.6974 / 24.2No
3836832D structureCHEMBL276272C32H37N7O2551.6956 / 35.0No
3861762D structureGhrp-6C46H56N12O6873.0329 / 111.9No
5552372D structuregrowth hormone releasing hexapeptideC46H56N12O6873.0329 / 111.9No
3896462D structureCHEMBL1080939C26H23ClN4O2458.9463 / 14.1Yes
3916992D structureCHEMBL277571C36H37N7O2599.7396 / 35.6No
3971472D structureCHEMBL1087908C26H23FN4O2442.4944 / 13.5Yes
4012382D structureCHEMBL274341C31H35N7O3553.6677 / 43.3No
5124882D structureCHEMBL3586019C79H109N19O121516.8615 / 163.4No
4029442D structureCHEMBL121803C29H40N4O4508.6635 / 22.4No
5129422D structureCHEMBL3593632C34H36N4O5580.6857 / 24.5No

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