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GPCR

NameG-protein coupled receptor 39
SpeciesHomo sapiens (Human)
GeneGPR39
SynonymGPR39
DiseaseDiabetes
Length453
Amino acid sequenceMASPSLPGSDCSQIIDHSHVPEFEVATWIKITLILVYLIIFVMGLLGNSATIRVTQVLQKKGYLQKEVTDHMVSLACSDILVFLIGMPMEFYSIIWNPLTTSSYTLSCKLHTFLFEACSYATLLHVLTLSFERYIAICHPFRYKAVSGPCQVKLLIGFVWVTSALVALPLLFAMGTEYPLVNVPSHRGLTCNRSSTRHHEQPETSNMSICTNLSSRWTVFQSSIFGAFVVYLVVLLSVAFMCWNMMQVLMKSQKGSLAGGTRPPQLRKSESEESRTARRQTIIFLRLIVVTLAVCWMPNQIRRIMAAAKPKHDWTRSYFRAYMILLPFSETFFYLSSVINPLLYTVSSQQFRRVFVQVLCCRLSLQHANHEKRLRVHAHSTTDSARFVQRPLLFASRRQSSARRTEKIFLSTFQSEAEPQSKSQSLSLESLEPNSGAKPANSAAENGFQEHEV
UniProtO43194
Protein Data BankN/A
GPCR-HGmod modelO43194
3D structure modelThis predicted structure model is from GPCR-EXP O43194.
BioLiPN/A
Therapeutic Target DatabaseT88531
ChEMBLCHEMBL3091266
IUPHAR105
DrugBankN/A

Known ligands

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Total entries: 29
Page:  / 1 

GLASS IDMoleculeFormulaMolecular weightH-bond acceptor / donorXlogPLipinski's druglikeness
237952D structureCHEMBL3092412C28H33N3O2443.5914 / 14.3Yes
4433442D structureCHEMBL3342375C18H19N5O2S369.4437 / 22.2Yes
4443442D structureGPR39-C3C18H19ClN6O2S418.98 / 32.6Yes
4451052D structureGSK137647AC16H19NO3S305.3924 / 13.5Yes
4456922D structureCHEMBL3342377C19H20N6O348.416 / 32.1Yes
4457772D structureCHEMBL3342372C17H15ClN4310.7854 / 13.7Yes
4460782D structureCHEMBL3342374C18H16F3N5O375.3559 / 24.1Yes
4462232D structureCHEMBL3342379C19H19FN6O366.47 / 32.2Yes
1204082D structureCHEMBL3342370C17H15Cl2N5360.2425 / 24.2Yes
4471012D structureCHEMBL3342362C21H20F3N5O415.429 / 24.9Yes
4475272D structureCHEMBL3342365C15H21N5271.3685 / 23.2Yes
4476822D structureZinkchloridCl2Zn136.282 / 0N/AN/A
4481072D structureCHEMBL3342363C13H14N4226.2834 / 11.9Yes
4494662D structureCHEMBL3342369C20H22N6O362.4376 / 22.3Yes
4496252D structureCHEMBL3342367C17H16ClN5325.85 / 23.6Yes
4497062D structureCHEMBL3342361C16H21N5O299.3786 / 22.1Yes
4503082D structureCHEMBL3342366C17H23N5297.4065 / 23.8Yes
4520432D structureCHEMBL3342373C20H20ClN5365.8655 / 24.3Yes
4522542D structureCHEMBL3342378C19H20N6O348.416 / 32.2Yes
4615372D structurezinc ionZn+265.380 / 0N/AN/A
4524702D structureCHEMBL3342368C16H16N6292.3466 / 21.9Yes
4529862D structureCHEMBL3342364C15H19N5269.3525 / 12.3Yes
4544932D structureCHEMBL3342360C18H25N5311.4335 / 23.9Yes
3361182D structureCHEMBL3092413C18H17ClN6352.8265 / 02.8Yes
4570922D structureCHEMBL3342371C18H15ClF3N5393.7988 / 24.7Yes
4577572D structureCHEMBL3342359C14H17N5255.3255 / 22.2Yes
4046482D structureCHEMBL3092411C23H26ClN5O423.9454 / 22.6Yes
4046492D structureCHEMBL3092410C23H26ClN5O423.9454 / 22.6Yes
4582072D structureCHEMBL3342376C18H20N6O2S384.4588 / 31.9Yes

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