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BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

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GPCR

NameNeurotensin receptor type 1
SpeciesRattus norvegicus (Rat)
GeneNtsr1
SynonymNTS1 receptor
NTRH
NTR1
NTR
NT-R-1
[ Show all ]
DiseaseN/A for non-human GPCRs
Length424
Amino acid sequenceMHLNSSVPQGTPGEPDAQPFSGPQSEMEATFLALSLSNGSGNTSESDTAGPNSDLDVNTDIYSKVLVTAIYLALFVVGTVGNSVTAFTLARKKSLQSLQSTVHYHLGSLALSDLLILLLAMPVELYNFIWVHHPWAFGDAGCRGYYFLRDACTYATALNVASLSVERYLAICHPFKAKTLMSRSRTKKFISAIWLASALLAIPMLFTMGLQNRSGDGTHPGGLVCTPIVDTATVKVVIQVNTFMSFLFPMLVISILNTVIANKLTVMVHQAAEQGRVCTVGTHNGLEHSTFNMTIEPGRVQALRHGVLVLRAVVIAFVVCWLPYHVRRLMFCYISDEQWTTFLFDFYHYFYMLTNALFYVSSAINPILYNLVSANFRQVFLSTLACLCPGWRHRRKKRPTFSRKPNSMSSNHAFSTSATRETLY
UniProtP20789
Protein Data Bank3zev, 4buo, 4bv0, 4bwb, 5t04
GPCR-HGmod modelN/A
3D structure modelThis structure is from PDB ID 3zev.
BioLiPBL0365097, BL0267346,BL0267350, BL0267315,BL0267316, BL0267314,BL0267317, BL0267354,BL0267355, BL0267356,BL0267357, BL0365096, BL0267347,BL0267348,BL0267349,
Therapeutic Target DatabaseN/A
ChEMBLCHEMBL3027
IUPHAR309
DrugBankN/A

Known ligands

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Total entries: 96
Page:  / 1 

GLASS IDMoleculeFormulaMolecular weightH-bond acceptor / donorXlogPLipinski's druglikeness
183922D structureCHEMBL8454C32H52N6O7632.8039 / 7-1.8No
230482D structureCHEMBL1794000C37H55FN6O8730.87910 / 72.5No
233002D structureCHEMBL1794002C38H57N5O8711.9019 / 73.0No
5534012D structureEISAI-1C43H71N11O7854.11110 / 92.5No
284432D structureCHEMBL3290100C29H29N3O4483.5685 / 26.4No
322602D structureCHEMBL3290101C29H29N3O5499.5676 / 25.6No
349072D structureCHEMBL21521C41H62N6O7750.9829 / 84.0No
363402D structureCHEMBL3290096C28H27ClN4O5534.9977 / 25.2No
365602D structureCHEMBL278301C43H63F3N6O9865.00514 / 9N/ANo
489642D structureCHEMBL3290099C30H31N3O5513.5946 / 26.4No
505682D structureCHEMBL1790472C37H60N6O8716.9219 / 7-0.1No
550812D structureCHEMBL38243C23H22N2O4S422.4996 / 23.6Yes
613482D structureCHEMBL3290105C25H26FN3O5467.4977 / 24.4Yes
616372D structureCHEMBL21892C45H67N11O6858.1028 / 105.5No
655532D structureCHEMBL1790473C34H54N6O8674.849 / 7-1.5No
662042D structureCHEMBL342252C38H64N12O8817.00611 / 11-4.0No
4710902D structureneurotensin (8-13)C38H64N12O8817.00611 / 11-4.0No
679312D structureCHEMBL1790465C45H60N6O8813.0099 / 73.5No
681312D structureCHEMBL1172376C41H70ClN9O8852.51610 / 8N/ANo
703312D structureCHEMBL1790463C42H64N6O8781.0089 / 72.4No
4445202D structureCHEMBL3356853C24H24ClN3O5469.9227 / 24.6Yes
720652D structureMeclinertantC32H31ClN4O5587.0737 / 25.8No
5536292D structure[3H]reminertantC32H31ClN4O5599.1217 / 25.8No
724312D structureCHEMBL1790466C38H55N7O8737.89910 / 70.8No
799362D structureCHEMBL1790476C50H86N6O8899.2729 / 78.6No
827312D structureCHEMBL3290106C24H24FN3O4437.4716 / 24.4Yes
4748532D structureCHEMBL3622803C38H68N8O8Si2821.1811 / 9N/ANo
1136612D structureCHEMBL3290091C29H29ClN4O5549.0247 / 26.0No
1181032D structureCHEMBL427656C36H58N6O9718.89310 / 7-0.5No
4775182D structureCHEMBL3622802C38H66N8O8Si791.07911 / 9N/ANo
1200452D structureCHEMBL8857C37H60N6O9732.9210 / 71.6No
1298302D structureCHEMBL3290097C27H25ClN4O5520.977 / 24.7No
1385042D structureBDBM50281810C39H62N6O9758.95811 / 61.9No
1458582D structureCHEMBL3290095C29H29ClN4O5549.0247 / 25.7No
4818362D structureCHEMBL3622804C40H72N8O8Si2849.23411 / 9N/ANo
1561582D structureCHEMBL1793999C37H55FN6O7714.889 / 62.9No
4829982D structureCHEMBL3622805C39H68N10O8Si833.1211 / 10N/ANo
1739662D structureCHEMBL1793838C38H66N12O7803.02311 / 11-2.2No
1807842D structureCHEMBL2371276C41H62N12O8851.02311 / 11-3.7No
1840752D structureCHEMBL1790469C40H51F15N6O81028.8624 / 75.3No
1969742D structureCHEMBL270332C76H124N16O141485.9318 / 164.4No
1983962D structureSR142948AC39H51N5O6685.8668 / 23.6No
2002362D structureCHEMBL3290103C29H30FN3O5519.5737 / 25.0No
2007342D structureCHEMBL266981C39H65N13O7828.03312 / 11-2.4No
2007352D structureCHEMBL3143475C39H65N13O7828.03312 / 11-2.4No
2007362D structureCHEMBL7384C39H65N13O7828.03312 / 11-2.4No
2007372D structureCHEMBL3143244C39H65N13O7828.03312 / 11-2.4No
2017262D structureCHEMBL2369588C41H64N6O8768.9979 / 72.6No
2059702D structureCHEMBL1790470C31H50N6O7618.7769 / 7-2.1No
4497972D structureCHEMBL3356855C25H26ClN3O5483.9497 / 25.4No
2092792D structureCHEMBL269581C37H61N7O9747.93512 / 81.0No
2119132D structureCID 44265524C39H62N6O9758.95811 / 72.8No
2267992D structureCHEMBL1790457C42H66N8O9S859.09711 / 90.7No
2295212D structureCHEMBL21892C47H68F3N11O8972.12513 / 11N/ANo
2320062D structureCHEMBL1790460C39H56N6O8736.9119 / 71.8No
2339012D structureCHEMBL1172376C41H70N9O8+817.0669 / 82.8No
2358192D structureCHEMBL1794003C37H56N6O8712.8899 / 72.4No
4515142D structureCHEMBL3403508C24H24FN3O4437.4716 / 25.4No
2563482D structureNEUROTENSINC78H121N21O201672.9523 / 21-3.7No
2564982D structureCHEMBL1790467C43H64N6O8793.0199 / 73.5No
2714752D structureSR-48527C29H29ClN4O5549.0247 / 26.0No
2808222D structureCHEMBL21521C43H63F3N6O9865.00514 / 9N/ANo
4529382D structureCHEMBL3356854C23H24ClN3O5457.9117 / 24.7Yes
2856452D structureCHEMBL1790461C38H62N6O8730.9489 / 71.5No
2891332D structureCHEMBL1793837C41H64N12O7837.0411 / 11-2.0No
2986162D structureCHEMBL3290092C28H27ClN4O4518.9986 / 26.0No
3007122D structureCHEMBL3290098C27H25ClN4O4504.9716 / 25.2No
3099412D structureCHEMBL8899C37H61N7O9747.93512 / 81.0No
4543932D structureCHEMBL3326831C25H26F3N3O6S553.55310 / 34.5No
3212962D structureCHEMBL415303C42H63N11O8850.03511 / 10-2.0No
3212972D structureCHEMBL7405C42H63N11O8850.03511 / 10-2.0No
3212982D structureCHEMBL266131C42H63N11O8850.03511 / 10-2.0No
3212992D structureCHEMBL274093C42H63N11O8850.03511 / 10-2.0No
3213002D structureCHEMBL3143232C42H63N11O8850.03511 / 10-2.0No
5031002D structureCHEMBL3622801C38H66N8O8Si791.07911 / 9N/ANo
5549242D structureJmv 449C38H66N8O7746.99511 / 9-0.3No
3324762D structureCHEMBL21448C45H67F3N10O9949.08714 / 11N/ANo
4549132D structureCHEMBL3403507C25H26FN3O5467.4977 / 25.3No
4549542D structureCHEMBL3403504C29H31ClN4O4535.0417 / 23.5No
3353072D structureCHEMBL1793998C37H55FN6O8730.87910 / 72.5No
3375832D structureCHEMBL2372106C43H66N6O8795.0359 / 72.8No
3384252D structureCHEMBL2369587C42H66N6O8783.0249 / 73.1No
3387482D structureCHEMBL3290102C28H27N3O4469.5415 / 25.6No
3636322D structureCHEMBL1793833C37H58N6O7698.9069 / 73.2No
3779492D structureCHEMBL21448C43H66N10O7835.0649 / 105.0No
3850482D structureCHEMBL3290104C26H28FN3O5481.5247 / 25.2No
4569852D structureCHEMBL3403505C28H27ClN4O5534.9977 / 26.1No
3864532D structureCHEMBL3290094C31H33ClN4O5577.0787 / 26.8No
3929302D structureCHEMBL7674C42H63N11O8850.03511 / 10-3.5No
3929312D structureCHEMBL269292C42H63N11O8850.03511 / 10-3.5No
3929322D structureCHEMBL3143334C42H63N11O8850.03511 / 10-3.5No
3936422D structureCHEMBL3290093C27H23ClF2N4O3524.9537 / 26.3No
4012772D structureCHEMBL1793839C41H62N12O8851.02311 / 11-2.2No
4577342D structureCHEMBL3326832C23H27N3O5S457.5456 / 33.7Yes
4056552D structureCHEMBL3290090C29H29ClN4O5549.0247 / 26.0No
4592282D structureCHEMBL3403506C29H29N3O5499.5676 / 26.5No

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