You can:
| Name | Type-1A angiotensin II receptor |
|---|---|
| Species | Rattus norvegicus (Rat) |
| Gene | Agtr1 |
| Synonym | Angiotensin II type-1A receptor AT1A |
| Disease | N/A for non-human GPCRs |
| Length | 359 |
| Amino acid sequence | MALNSSAEDGIKRIQDDCPKAGRHSYIFVMIPTLYSIIFVVGIFGNSLVVIVIYFYMKLKTVASVFLLNLALADLCFLLTLPLWAVYTAMEYRWPFGNHLCKIASASVSFNLYASVFLLTCLSIDRYLAIVHPMKSRLRRTMLVAKVTCIIIWLMAGLASLPAVIHRNVYFIENTNITVCAFHYESRNSTLPIGLGLTKNILGFLFPFLIILTSYTLIWKALKKAYEIQKNKPRNDDIFRIIMAIVLFFFFSWVPHQIFTFLDVLIQLGVIHDCKISDIVDTAMPITICIAYFNNCLNPLFYGFLGKKFKKYFLQLLKYIPPKAKSHSSLSTKMSTLSYRPSDNMSSSAKKPASCFEVE |
| UniProt | P25095 |
| Protein Data Bank | N/A |
| GPCR-HGmod model | N/A |
| 3D structure model | No available structures or models |
| BioLiP | N/A |
| Therapeutic Target Database | N/A |
| ChEMBL | CHEMBL329 |
| IUPHAR | 34 |
| DrugBank | N/A |
You can:
| GLASS ID | Molecule | Formula | Molecular weight | H-bond acceptor / donor | XlogP | Lipinski's druglikeness |
|---|---|---|---|---|---|---|
| 1988 |  valsartan | C24H29N5O3 | 435.528 | 6 / 2 | 4.4 | Yes |
| 6031 |  141872-46-0 | C23H23N7O2 | 429.484 | 8 / 2 | 3.8 | Yes |
| 7768 |  selenoeprosartan | C23H24N2O4Se | 471.426 | 5 / 2 | N/A | N/A |
| 12157 |  CHEMBL396849 | C24H34N2O6S2 | 510.664 | 7 / 1 | 5.7 | No |
| 15004 |  CHEMBL2260200 | C32H26N4O4 | 530.584 | 6 / 0 | 5.5 | No |
| 15757 |  CID 44450235 | C24H22N6O | 410.481 | 5 / 1 | 3.6 | Yes |
| 19057 |  CHEMBL565379 | C24H30N2O3 | 394.515 | 4 / 0 | 5.4 | No |
| 19360 |  CHEMBL481089 | C23H32N2O5S2 | 480.638 | 6 / 2 | 5.7 | No |
| 27023 |  CHEMBL246253 | C27H34N2O5S3 | 562.758 | 7 / 1 | 6.9 | No |
| 28563 |  CHEMBL408227 | C24H22ClN7O | 459.938 | 6 / 1 | 5.3 | No |
| 34516 |  CHEMBL259114 | C24H23N7O | 425.496 | 6 / 1 | 4.3 | Yes |
| 34672 |  CHEMBL246461 | C22H32N2O4S2 | 452.628 | 6 / 1 | 5.4 | No |
| 43584 |  CHEMBL481106 | C24H32N2O6S2 | 508.648 | 7 / 1 | 4.7 | No |
| 45669 |  CHEMBL480018 | C26H27N3O4S | 477.579 | 6 / 2 | 4.9 | Yes |
| 46122 |  CHEMBL239396 | C21H30N2O5S3 | 486.66 | 7 / 1 | 4.6 | Yes |
| 46453 |  CHEMBL265958 | C25H26N8O | 454.538 | 7 / 2 | 4.6 | Yes |
| 48222 |  CHEMBL246460 | C22H30N2O5S2 | 466.611 | 6 / 1 | 4.9 | Yes |
| 49983 |  CHEMBL437377 | C24H34N2O5S2 | 494.665 | 6 / 1 | 5.3 | No |
| 52641 |  CHEMBL2260194 | C31H26N4O2 | 486.575 | 4 / 0 | 6.1 | No |
| 53189 |  CHEMBL517230 | C27H29N3O4S | 491.606 | 6 / 2 | 5.2 | No |
| 53672 |  CHEMBL342261 | C23H25N3O4 | 407.47 | 6 / 3 | 4.5 | Yes |
| 53673 |  CHEMBL2111971 | C23H25N3O4 | 409.478 | 6 / 3 | 4.5 | Yes |
| 54286 |  CHEBI:58506 | C50H71N13O12 | 1046.2 | 13 / 12 | -0.4 | No |
| 56237 |  CHEMBL245840 | C32H42N2O5S2 | 598.817 | 6 / 1 | 7.7 | No |
| 60405 |  CHEMBL409744 | C23H21N7O | 411.469 | 6 / 1 | 4.0 | Yes |
| 61604 |  CID 24828709 | C23H20N6O | 396.454 | 5 / 1 | 3.2 | Yes |
| 63113 |  Abbott-81988 | C23H22N6O2 | 414.469 | 7 / 2 | 4.1 | Yes |
| 64480 |  CHEMBL247079 | C27H40N2O5S2 | 536.746 | 6 / 2 | 7.1 | No |
| 67140 |  CHEMBL2373017 | C43H65N13O10S2 | 988.194 | 15 / 12 | -2.8 | No |
| 553601 |  Saprisartan | C25H22BrF3N4O4S | 611.434 | 9 / 2 | 5.2 | No |
| 69249 |  CHEMBL246877 | C28H34N2O5S2 | 542.709 | 6 / 2 | 6.7 | No |
| 70236 |  CHEMBL471505 | C29H31N3O3 | 469.585 | 4 / 2 | 5.9 | No |
| 74385 |  CHEMBL430388 | C29H36N2O5S2 | 556.736 | 6 / 1 | 6.4 | No |
| 76996 |  CHEMBL344464 | C29H29ClN4O5S | 581.084 | 7 / 3 | 6.0 | No |
| 76997 |  CHEMBL2111973 | C29H29ClN4O5S | 583.092 | 7 / 3 | 6.0 | No |
| 82510 |  CHEMBL358359 | C26H30N6O2 | 458.566 | 5 / 1 | 4.1 | Yes |
| 84325 |  CHEMBL246254 | C26H38N2O5S2 | 522.719 | 6 / 1 | 6.3 | No |
| 89396 |  CHEMBL2260199 | C34H30N4O4 | 558.638 | 6 / 2 | 6.4 | No |
| 553703 |  5-oxo-1-2-4-oxadiazol biphenyl | C23H25N3O5 | 423.469 | 6 / 2 | 3.7 | Yes |
| 90051 |  CHEMBL241697 | C21H30N2O6S2 | 470.599 | 7 / 1 | 4.0 | Yes |
| 91293 |  CHEMBL480341 | C23H27N3O5S3 | 521.665 | 8 / 2 | 5.8 | No |
| 91431 |  L-162782 | C32H40N4O4S | 576.756 | 6 / 1 | 7.5 | No |
| 93194 |  CHEMBL410105 | C25H25N7O | 439.523 | 6 / 1 | 4.7 | Yes |
| 94682 |  CHEMBL567898 | C30H32N8O | 520.641 | 6 / 1 | 5.6 | No |
| 95841 |  CHEMBL480507 | C22H28N2O5S | 432.535 | 5 / 1 | 4.1 | Yes |
| 99038 |  CHEMBL1237157 | C23H24ClN7O2 | 465.942 | 8 / 3 | N/A | N/A |
| 99383 |  CHEMBL1237156 | C24H26ClN7O2 | 479.969 | 8 / 3 | N/A | N/A |
| 524445 |  CHEMBL3787059 | C23H21ClN4O4 | 452.895 | 6 / 2 | 5.3 | No |
| 102291 |  CHEMBL394734 | C33H36N2O5S2 | 604.78 | 6 / 1 | 8.1 | No |
| 105004 |  CHEMBL271264 | C30H30N6O3Se | 601.58 | 7 / 1 | N/A | No |
| 115334 |  CHEMBL408188 | C24H22FN7O | 443.486 | 7 / 1 | 4.4 | Yes |
| 118647 |  CHEMBL571763 | C39H42N4O4 | 630.789 | 6 / 0 | 8.2 | No |
| 123752 |  candesartan | C24H20N6O3 | 440.463 | 7 / 2 | 4.1 | Yes |
| 127305 |  CHEMBL397084 | C22H30N2O5S2 | 466.611 | 6 / 2 | 4.7 | Yes |
| 127361 |  CHEMBL131365 | C27H27N3O3 | 441.531 | 4 / 2 | 5.1 | No |
| 130022 |  CHEMBL246667 | C28H34N2O5S2 | 542.709 | 6 / 2 | 6.3 | No |
| 131242 |  CHEMBL217673 | C25H31N3O4S | 469.6 | 5 / 1 | 5.2 | No |
| 135921 |  CHEMBL247482 | C33H37N3O5S2 | 619.795 | 7 / 1 | 7.0 | No |
| 136398 |  CHEMBL255532 | C30H30N6O3S | 554.669 | 8 / 1 | 5.3 | No |
| 145326 |  CHEMBL257870 | C28H28N6OSe | 543.544 | 5 / 1 | N/A | No |
| 146363 |  CHEMBL517685 | C24H32N2O5S2 | 492.649 | 6 / 1 | 5.5 | No |
| 146824 |  CHEMBL260578 | C25H23N7O2 | 453.506 | 7 / 1 | 4.1 | Yes |
| 147096 |  CHEMBL246875 | C30H38N2O5S2 | 570.763 | 6 / 1 | 6.8 | No |
| 148152 |  CHEMBL480340 | C28H34N2O5S2 | 542.709 | 6 / 1 | 6.5 | No |
| 152059 |  CHEMBL519274 | C23H30N2O5S2 | 478.622 | 6 / 2 | 5.4 | No |
| 152578 |  CHEMBL521093 | C24H34N2O5S2 | 494.665 | 6 / 1 | 5.8 | No |
| 153398 |  CHEMBL259116 | C24H23N7O | 425.496 | 6 / 1 | 4.4 | Yes |
| 153795 |  CHEMBL584704 | C31H36N2O4 | 500.639 | 5 / 0 | 7.0 | No |
| 154635 |  CHEMBL2260192 | C33H28N4O4 | 544.611 | 6 / 0 | 5.9 | No |
| 162755 |  CHEMBL246255 | C23H32N2O5S2 | 480.638 | 6 / 1 | 4.9 | Yes |
| 164819 |  CHEMBL2260190 | C30H24N4O2 | 472.548 | 4 / 0 | 5.7 | No |
| 167838 |  CHEMBL518230 | C28H31N3O4S | 505.633 | 6 / 2 | 5.7 | No |
| 167893 |  CHEMBL128318 | C25H25N3O2 | 399.494 | 4 / 2 | 5.2 | No |
| 170949 |  CHEMBL246043 | C29H36N2O5S2 | 556.736 | 6 / 1 | 6.8 | No |
| 173541 |  CHEMBL410125 | C25H24N6O | 424.508 | 5 / 1 | 5.1 | No |
| 176629 |  CHEMBL419684 | C26H29ClN2O2 | 436.98 | 4 / 1 | 5.4 | No |
| 177922 |  CHEMBL265208 | C25H25N7O | 439.523 | 6 / 1 | 4.7 | Yes |
| 186340 |  CHEMBL480506 | C29H34N2O5S | 522.66 | 5 / 1 | 6.1 | No |
| 186735 |  CHEMBL465929 | C29H33N3O4S | 519.66 | 6 / 2 | 6.1 | No |
| 186831 |  CHEMBL258685 | C25H25N7O | 439.523 | 6 / 1 | 4.9 | Yes |
| 195067 |  CHEMBL261765 | C25H25N7O | 439.523 | 6 / 1 | 4.8 | Yes |
| 197814 |  CHEMBL315444 | C25H28N6O2 | 444.539 | 5 / 1 | 4.3 | Yes |
| 200948 |  SCHEMBL6448917 | C31H31N3O5S | 557.665 | 7 / 1 | 6.2 | No |
| 204756 |  CHEMBL481664 | C29H34N2O5S | 522.66 | 5 / 1 | 6.1 | No |
| 207207 |  CHEMBL239393 | C23H32N2O5S2 | 480.638 | 6 / 1 | 5.0 | Yes |
| 207250 |  CHEMBL520421 | C26H36N2O5S2 | 520.703 | 6 / 2 | 6.7 | No |
| 213547 |  CHEMBL395387 | C28H35N3O5S2 | 557.724 | 7 / 1 | 5.3 | No |
| 214661 |  CHEMBL258684 | C27H21N7O | 459.513 | 6 / 1 | 4.6 | Yes |
| 216861 |  CHEMBL246876 | C25H34N2O6S2 | 522.675 | 7 / 1 | 4.6 | No |
| 217110 |  CHEMBL481294 | C26H36N2O5S | 488.643 | 5 / 1 | 5.7 | No |
| 217726 |  CHEMBL392514 | C22H30N2O5S2 | 466.611 | 6 / 2 | 4.8 | Yes |
| 221257 |  CHEMBL259353 | C24H23N7O | 425.496 | 6 / 1 | 4.3 | Yes |
| 222440 |  CHEMBL2260195 | C28H22N4 | 414.512 | 2 / 0 | 5.8 | No |
| 224517 |  CHEMBL486847 | C32H29N3O3 | 503.602 | 4 / 2 | 6.8 | No |
| 224851 |  CHEMBL480017 | C25H25N3O4S | 463.552 | 6 / 2 | 4.5 | Yes |
| 226336 |  CHEMBL409722 | C24H23N7O | 425.496 | 6 / 1 | 4.7 | Yes |
| 230387 |  CHEMBL246044 | C35H40N2O5S2 | 632.834 | 6 / 1 | 8.0 | No |
| 241630 |  CHEMBL480122 | C28H32N2O5S | 508.633 | 5 / 1 | 5.8 | No |
| 247345 |  CHEMBL567063 | C23H26N2O2 | 362.473 | 3 / 0 | 5.2 | No |
| 247967 |  SCHEMBL6447967 | C25H26BrN3O5S | 560.463 | 7 / 1 | 5.3 | No |
zhanglab
zhanggroup.org | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218