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GPCR

NameMuscarinic acetylcholine receptor M4
SpeciesMus musculus (Mouse)
GeneChrm4
Synonymcholinergic receptor
cholinergic receptor, muscarinic 4
Chrm-4
HM3
M4 receptor
[ Show all ]
DiseaseN/A for non-human GPCRs
Length479
Amino acid sequenceMANFTPVNGSSANQSVRLVTTAHNHLETVEMVFIATVTGSLSLVTVVGNILVMLSIKVNRQLQTVNNYFLFSLACADLIIGAFSMNLYTLYIIKGYWPLGAVVCDLWLALDYVVSNASVMNLLIISFDRYFCVTKPLTYPARRTTKMAGLMIAAAWVLSFVLWAPAILFWQFVVGKRTVPDNQCFIQFLSNPAVTFGTAIAAFYLPVVIMTVLYIHISLASRSRVHKHRPEGPKEKKAKTLAFLKSPLMKPSIKKPPPGGASREELRNGKLEEAPPPALPPPPRPVADKDTSNESSSGSATQNTKERPPTELSTTEAATTPALPAPTLQPRTLNPASKWSKIQIVTKQTGSECVTAIEIVPATPAGMRPAANVARKFASIARNQVRKKRQMAARERKVTRTIFAILLAFILTWTPYNVMVLVNTFCQSCIPERVWSIGYWLCYVNSTINPACYALCNATFKKTFRHLLLCQYRNIGTAR
UniProtP32211
Protein Data BankN/A
GPCR-HGmod modelN/A
3D structure modelNo available structures or models
BioLiPN/A
Therapeutic Target DatabaseN/A
ChEMBLCHEMBL4572
IUPHARN/A
DrugBankN/A

Known ligands

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Total entries: 8
Page:  / 1 

GLASS IDMoleculeFormulaMolecular weightH-bond acceptor / donorXlogPLipinski's druglikeness
821272D structureHimbacineC22H35NO2345.5273 / 05.0Yes
821502D structureHimbacineC22H35NO2345.5273 / 05.0Yes
843042D structure633283-39-3C17H16ClN3OS345.8454 / 24.6Yes
1271002D structure4-Diphenylacetoxy-1,1-dimethylpiperidiniumC21H26NO2+324.4442 / 04.0Yes
2862092D structurehexahydrosiladifenidolC20H33NOSi331.5752 / 1N/AN/A
2997362D structurepirenzepineC19H21N5O2351.415 / 10.1Yes
3020052D structureMethoctramineC36H62N4O2582.9186 / 46.8No
3329032D structureOtenzepadC24H31N5O2421.5455 / 12.0Yes

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