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BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

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GPCR

NameD(3) dopamine receptor
SpeciesChlorocebus aethiops (Green monkey)
GeneDRD3
SynonymDopamine D3 receptor
DiseaseN/A for non-human GPCRs
Length400
Amino acid sequenceMAPLSQLSGHLNYTCGVENSTGASQARPHAYYALSYCALILAIVFGNGLVCMAVLKERALQTTTNYLVVSLAVADLLVATLVMPWVVYLEVTGGVWNFSRVCCDVFVTLDVMMCTASILNLCAISIDRYTAVVMPVHYQHGTGQSSCRRVTLMITAVWVLAFAVSCPLLFGFNTTGDPTVCSISNPDFVIYSSVVSFYLPFGVTVLVYARIYVVLKQRRRKRILTRQNSQCNSVRPGFPQQTLSPDRAHLELKRYYSICQDTALGGPGFQERGGELKREERTRNSLSPTIAPKLSLEVRKLSNGRLSTSLKLGPLQPRGVPLREKKATQMVAIVLGAFIVCWLPFFLTHVLNTHCQTCHVSPELYSATTWLGYVNSALNPVIYTTFNIEFRKAFLKILSC
UniProtP52703
Protein Data BankN/A
GPCR-HGmod modelN/A
3D structure modelNo available structures or models
BioLiPN/A
Therapeutic Target DatabaseN/A
ChEMBLCHEMBL2304406
IUPHARN/A
DrugBankN/A

Known ligands

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Total entries: 14
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GLASS IDMoleculeFormulaMolecular weightH-bond acceptor / donorXlogPLipinski's druglikeness
726522D structureCHEMBL356542C24H26N4O386.4993 / 13.5Yes
727482D structureCHEMBL146557C23H24N4O372.4722 / 13.9Yes
1019682D structureCHEMBL343466C20H22N4318.4243 / 03.0Yes
1056412D structureRemoxiprideC16H23BrN2O3371.2754 / 12.1Yes
1915932D structurehaloperidolC21H23ClFNO2375.8684 / 13.2Yes
1995922D structureCHEMBL147731C22H22N2314.4321 / 04.0Yes
2096552D structureBP 897C26H31N3O2417.5534 / 14.8Yes
2251362D structureCHEMBL343657C21H23N3317.4362 / 03.7Yes
2729492D structureCHEMBL27254C22H28IN3O2493.3894 / 14.2Yes
5663742D structureclozapineC18H19ClN4326.8283 / 13.1Yes
3285592D structureCHEMBL446892C23H23F3N2O400.4455 / 14.2Yes
3426272D structureCHEMBL28321C22H25N3O347.4623 / 03.7Yes
3454722D structureCHEMBL144835C22H24N2316.4481 / 04.4Yes
3521772D structureCHEMBL147003C22H23ClN2O366.8892 / 13.9Yes

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