Home Research COVID-19 Services Publications People Teaching Job Opening News Forum Lab Only
Online Services

I-TASSER I-TASSER-MTD C-I-TASSER CR-I-TASSER QUARK C-QUARK LOMETS MUSTER CEthreader SEGMER DeepFold DeepFoldRNA FoldDesign COFACTOR COACH MetaGO TripletGO IonCom FG-MD ModRefiner REMO DEMO DEMO-EM SPRING COTH Threpp PEPPI BSpred ANGLOR EDock BSP-SLIM SAXSTER FUpred ThreaDom ThreaDomEx EvoDesign BindProf BindProfX SSIPe GPCR-I-TASSER MAGELLAN ResQ STRUM DAMpred

TM-score TM-align US-align MM-align RNA-align NW-align LS-align EDTSurf MVP MVP-Fit SPICKER HAAD PSSpred 3DRobot MR-REX I-TASSER-MR SVMSEQ NeBcon ResPRE TripletRes DeepPotential WDL-RF ATPbind DockRMSD DeepMSA FASPR EM-Refiner GPU-I-TASSER

BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

You can:

GPCR

NameSubstance-K receptor
SpeciesOryctolagus cuniculus (Rabbit)
GeneTACR2
SynonymNeurokinin A receptor
NK-2 receptor
NK-2R
SKR
Tachykinin receptor 2
DiseaseN/A for non-human GPCRs
Length384
Amino acid sequenceMGACDIVTEANISSDIDSNATGVTAFSMPGWQLALWATAYLALVLVAVVGNATVIWIILAHRRMRTVTNYFIVNLALADLCMATFNAAFNFVYASHNIWYFGRAFCYFQNLFPITAMFVSIYSMTAIAADRYMAIVHPFQPRLSGPGTKAVIAGIWLVALALAFPQCFYSTITMDQGATKCVVAWPEDSGGKMLLLYHLTVIALIYFLPLVVMFVAYSVIGFKLWRRTVPGHQTHGANLRHLRAKKKFVKTMVLVVVTFAVCWLPYHLYFLLGHFQDDIYCRKFIQQVYLVLFWLAMSSTMYNPIIYCCLNHRFRSGFRLAFRCCPWVTPTEEDKLELTHTPSLSVRVNRCHTKETLFLVGDVAPSEAANGQAGGPQDGGAYDF
UniProtP79218
Protein Data BankN/A
GPCR-HGmod modelN/A
3D structure modelNo available structures or models
BioLiPN/A
Therapeutic Target DatabaseN/A
ChEMBLCHEMBL3433
IUPHARN/A
DrugBankN/A

Known ligands

You can:

Total entries: 194
Page:  / 2 

GLASS IDMoleculeFormulaMolecular weightH-bond acceptor / donorXlogPLipinski's druglikeness
7762D structureCHEMBL408242C36H37Cl2N3O2S646.6715 / 07.5No
17212D structureCHEMBL2373196C34H36Cl2N2O2S607.6344 / 07.4No
84292D structureCHEMBL3144347C42H46N6O7746.8657 / 34.2No
5197332D structureCHEMBL45085C42H46N6O7746.8657 / 34.2No
129652D structureCHEMBL2370585C66H83N13O171330.4619 / 19-1.8No
130582D structureCHEMBL387699C38H44N6O4648.8085 / 54.3No
180012D structureCHEMBL161288C43H51N7O10825.9210 / 100.5No
180032D structureCHEMBL350596C43H51N7O10825.9210 / 100.5No
5197802D structureCHEMBL65468C39H35F6N8O5-809.7515 / 35.2No
201282D structureCHEMBL337435C35H39Cl2N5O5680.6277 / 14.6No
204722D structureCHEMBL329888C46H58N8O11S931.07513 / 110.6No
242022D structureCHEMBL2373189C34H36Cl2N2O2S607.6344 / 07.4No
283862D structureCHEMBL96794C35H35Cl2F3N2O2S675.6327 / 08.3No
307452D structureCHEMBL412621C60H64N10O121117.2313 / 143.2No
319702D structureCHEMBL128723C36H34Cl2N4O2S657.6546 / 06.8No
331822D structureCHEMBL341016C35H34Cl2FN3O2S650.6346 / 07.2No
362132D structureL-732,138C22H18F6N2O3472.3879 / 24.7Yes
375132D structureCHEMBL434548C28H39Cl2F2N3O2558.5366 / 15.1No
460262D structureCHEMBL332820C40H57N9O6759.9538 / 91.5No
461802D structureCHEMBL128782C33H37Cl2N5O3622.5915 / 15.7No
495852D structureCHEMBL387199C56H64N10O11S1085.2513 / 132.6No
497992D structureCHEMBL3144343C41H44N6O6716.8396 / 33.8No
5199112D structureCHEMBL296267C41H44N6O6716.8396 / 33.8No
518682D structureLANEPITANTC33H45N5O3559.7555 / 24.2No
518712D structureCHEMBL351236C33H45N5O3559.7555 / 24.2No
535112D structureCHEMBL161242C42H51N7O7765.9128 / 62.0No
537422D structureCHEMBL132347C35H34Cl2FN3O2S650.6346 / 07.2No
553322D structureCHEMBL128891C37H43Cl2N5O4692.6826 / 05.5No
553482D structureCHEMBL146796C38H41Cl2N3O2S674.7255 / 08.4No
581502D structureCHEMBL223644C37H43N7O4649.7966 / 62.8No
594152D structureCHEMBL411037C34H37Cl2N3O4S2686.7077 / 16.0No
629612D structureCHEMBL130085C34H37Cl2N5O4650.6016 / 14.6No
645372D structureCHEMBL433192C38H51N9O7745.8828 / 90.2No
646762D structureCHEMBL412189C60H64N10O111101.2312 / 133.5No
655492D structureCHEMBL268563C61H67N11O101114.2711 / 133.3No
682342D structureCHEMBL327457C48H59N9O10S954.11312 / 111.1No
685692D structureCP-99994C19H24N2O296.4143 / 22.9Yes
707812D structureCHEMBL421062C40H56N8O6744.9387 / 83.0No
734322D structureCHEMBL441181C50H60N10O11S1009.1513 / 130.3No
804002D structureCHEMBL438716C48H60N12O11981.08113 / 14-1.4No
804042D structureCHEMBL266526C48H60N12O11981.08113 / 14-1.4No
814332D structureCP 96345C28H32N2O412.5773 / 15.4No
854632D structureCHEMBL121271C47H56N8O6829.0157 / 84.5No
903882D structureCHEMBL340736C32H35Cl2N5O2592.5654 / 15.8No
931222D structureCHEMBL360134C28H39Cl2N3O2520.5394 / 04.5No
994792D structureCHEMBL2112922C44H53N7O5759.9526 / 54.5No
1027782D structureCHEMBL339575C36H35Cl2N3O4S676.6537 / 14.4No
1055922D structureCHEMBL185572C27H39Cl2N3O2508.5284 / 05.1No
1084392D structureCHEMBL185133C26H36Cl2FN3O496.4924 / 05.4No
1124552D structureCHEMBL3215392C46H56N8O13928.99714 / 13-1.7No
1125882D structureCHEMBL406487C57H67N13O111110.2413 / 150.8No
1125912D structureCHEMBL429340C57H67N13O111110.2413 / 150.8No
1125932D structureCHEMBL217365C57H67N13O111110.2413 / 150.8No
1138242D structureCHEMBL367815C28H37Cl2F2N3O2556.526 / 04.7No
5201912D structureCHEMBL297376C44H48N6O8788.9028 / 43.2No
1179492D structureCHEMBL3144351C44H48N6O8788.9028 / 43.2No
1193082D structureCHEMBL2373193C34H36Cl2N2O3S623.6334 / 07.5No
1259352D structureCHEMBL332872C38H50N8O8746.8669 / 9-1.4No
1317922D structureCHEMBL439287C62H65N11O111140.2712 / 143.7No
1384412D structureCHEMBL129117C35H35Cl2N3O3S648.6436 / 16.8No
1413532D structureCHEMBL130082C36H34Cl2N4O2S657.6546 / 06.8No
1436252D structureCHEMBL407328C57H68N14O101109.2612 / 150.1No
1503692D structureCHEMBL342758C41H39Cl2N3O2S708.7425 / 08.7No
1537332D structureCHEMBL389459C37H42N6O5650.786 / 53.1No
1537362D structureCHEMBL387698C37H42N6O5650.786 / 53.1No
1561472D structureCHEMBL2373191C34H40Cl2N4O3623.6194 / 15.6No
1562992D structureCHEMBL436388C36H36Cl2N4O3S675.6696 / 16.0No
1629102D structureCHEMBL339767C31H34Cl2N2O2S569.5854 / 06.1No
1704042D structureCHEMBL341175C36H41Cl2N5O3662.6565 / 05.5No
1713242D structureCHEMBL3215393C72H87N13O171406.5619 / 190.3No
1755732D structureCHEMBL322879C37H41Cl2N3O3S678.7135 / 06.9No
1778752D structureCHEMBL2112926C37H42N6O7682.7787 / 82.1No
1793042D structureCHEMBL333515C44H62N8O6799.037 / 74.9No
1800412D structureCHEMBL434142C28H40Cl2F2N4O557.5526 / 14.8No
1811792D structureCHEMBL267409C53H58N10O111011.1112 / 131.6No
1827902D structureCHEMBL2373197C31H36Cl2N4O2567.5553 / 16.0No
1838452D structureCHEMBL263743C51H64N12O111021.1513 / 13-0.7No
1847892D structureCHEMBL263985C59H68N14O101133.2812 / 151.2No
1847932D structureCHEMBL216897C59H68N14O101133.2812 / 151.2No
1850492D structureCHEMBL180049C27H39Cl2N3O2508.5284 / 04.6No
1880442D structureCHEMBL413730C51H64N10O141041.1316 / 15-0.7No
1885172D structureCHEMBL339213C35H34BrCl2N3O2S711.545 / 07.8No
5204652D structureCHEMBL437060C48H58N6O6815.0286 / 36.8No
1910462D structureCHEMBL3144339C48H58N6O6815.0286 / 36.8No
1993882D structureCHEMBL121571C39H54N8O6S762.9718 / 82.3No
2007412D structureCHEMBL2112924C41H48N6O10784.86710 / 100.5No
2050362D structureCHEMBL3215394C63H78N12O151243.3917 / 17-0.7No
2071522D structureCHEMBL129264C36H37Cl2N3O3S2694.737 / 06.2No
2076182D structureCHEMBL333027C48H63N9O8894.0879 / 93.6No
2083712D structureCHEMBL318364C36H36Cl2N2O2S631.6564 / 07.6No
2128242D structureCHEMBL357908C39H43Cl2N3O2S688.7525 / 08.7No
2143322D structureCHEMBL421071C43H58N8O7798.9867 / 84.2No
2144442D structureCHEMBL385914C55H63N11O111054.1813 / 14-1.5No
2186532D structureCHEMBL3144340C42H46N6O6730.8666 / 33.8No
5205732D structureCHEMBL46849C42H46N6O6730.8666 / 33.8No
2187082D structureMEN-10414C40H46N8O8766.8569 / 10-0.4No
2222882D structureCHEMBL2112923C39H44N6O6692.8176 / 52.4No
2306772D structureCHEMBL262647C54H70N12O101047.2313 / 14-2.0No
2310632D structureCHEMBL149326C37H39Cl2N3O2S660.6985 / 07.9No
2324252D structureCHEMBL92742C34H35BrCl2N2O2S686.534 / 08.1No

yangzhanglabzhanggroup.org | (734) 647-1549 | 100 Washtenaw Avenue, Ann Arbor, MI 48109-2218