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BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

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GPCR

NameMetabotropic glutamate receptor 1
SpeciesMus musculus (Mouse)
GeneGrm1
SynonymSCAR13
MGLUR1
mGlu1 receptor
metabotropic glutamate receptor 1
GPRC1A
[ Show all ]
DiseaseN/A for non-human GPCRs
Length1199
Amino acid sequenceMVRLLLIFFPMIFLEMSILPRMPDRKVLLAGASSQRSVARMDGDVIIGALFSVHHQPPAEKVPERKCGEIREQYGIQRVEAMFHTLDKINADPVLLPNITLGSEIRDSCWHSSVALEQSIEFIRDSLISIRDEKDGLNRCLPDGQTLPPGRTKKPIAGVIGPGSSSVAIQVQNLLQLFDIPQIAYSATSIDLSDKTLYKYFLRVVPSDTLQARAMLDIVKRYNWTYVSAVHTEGNYGESGMDAFKELAAQEGLCIAHSDKIYSNAGEKSFDRLLRKLRERLPKARVVVCFCEGMTVRGLLSAMRRLGVVGEFSLIGSDGWADRDEVIEGYEVEANGGITIKLQSPEVRSFDDYFLKLRLDTNTRNPWFPEFWQHRFQCRLPGHLLENPNFKKVCTGNESLEENYVQDSKMGFVINAIYAMAHGLQNMHHALCPGYVGLCDAMKPIDGRKLLDFLIKSSFVGVSGEEVWFDEKGDAPGRYDIMNLQYTEANRYDYVHVGTWHEGVLNIDDYKIQMNKSGMVRSVCSEPCLKGQIKVIRKGEVSCCWICTACKENEFVQDEFTCRACDLGWWPNAELTGCEPITIRYLEWSDIESIIAIAFSCLGILVTLFVTLIFVLYRDTPVVKSSSRELCYIILAGIFLGYVCPFTLIAKPTTTSCYLQRLLVGLSSAMCYSALVTKTNRIARILAGSKKKICTRKPRFMSAWAQVIIASILISVQLTLVVTLIIMEPPMPILSYPSIKEVYLICNTSNLGVVAPVGYNGLLIMSCTYYAFKTRNVPANFNEAKYIAFTMYTTCIIWLAFVPIYFGSNYKIITTCFAVSLSVTVALGCMFTPKMYIIIAKPERNVRSAFTTSDVVRMHVGDGKLPCRSNTFLNIFRRKKPGAGNANSNGKSVSWSEPGGRQAPKGQHVWQRLSVHVKTNETACNQTAVIKPLTKSYQGSGKSLTFSDASTKTLYNVEEEDNTPSTHFSPPSSPSMVVHRRGPPVATTPPLPPHLSAEETPLFLADSVIPKGLPPPLPQQQQQPPPQPPPQQPKSLMDQLQGVVTNFGSGIPDFHAVLAGPGTPGNGLRSLYPPPPPPQHLQMLPLQLSTFREEPISPPGEDDDDDSSERFKLLQEFVYEREGNTEEDDLEEEEDLPAASKLTPEDSPALTPPSPFRDSVASGSSVPSSPVSESVLCTPPNVTYASVILRDYKQSSSTL
UniProtP97772
Protein Data BankN/A
GPCR-HGmod modelN/A
3D structure modelNo available structures or models
BioLiPN/A
Therapeutic Target DatabaseN/A
ChEMBLCHEMBL2892
IUPHARN/A
DrugBankN/A

Known ligands

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Total entries: 17
Page:  / 1 

GLASS IDMoleculeFormulaMolecular weightH-bond acceptor / donorXlogPLipinski's druglikeness
135732D structureCHEMBL511355C18H22N4O2326.44 / 02.4Yes
362552D structureCHEMBL453249C17H21N5O2327.3885 / 01.4Yes
436902D structureFTIDCC18H23FN6O358.4215 / 01.6Yes
954372D structureCHEMBL461673C18H21FN4O2344.395 / 02.5Yes
1017192D structureCHEMBL460391C18H21FN4O2344.395 / 02.5Yes
1050712D structureCHEMBL457872C17H21N5O2327.3885 / 01.7Yes
1377152D structureCHEMBL456823C18H22FN5O2359.4056 / 02.2Yes
1544262D structureCHEMBL511352C19H24N4O2340.4274 / 02.8Yes
1773442D structureCHEMBL460827C18H21FN4O2344.395 / 02.5Yes
2157092D structureCHEMBL457026C16H18FN5O2331.3516 / 01.6Yes
2515222D structureCHEMBL456196C17H20FN5O2345.3786 / 02.0Yes
2984382D structureCHEMBL452618C17H20FN5O2345.3786 / 01.8Yes
3049632D structureFPTQC17H12FN5305.3165 / 03.0Yes
3601022D structureCHEMBL461034C18H22FN5O343.4064 / 12.0Yes
3860442D structureCHEMBL461035C19H23FN4O342.4184 / 02.8Yes
4085842D structureCHEMBL461033C19H24N4O3356.4265 / 02.4Yes
4230832D structureCHEMBL457873C17H21N5O2327.3885 / 01.4Yes

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