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GPCR

NameCorticotropin-releasing factor receptor 2
SpeciesMus musculus (Mouse)
GeneCrhr2
SynonymCRFR-2
CRFR2
CRFR2alpha
CRFR2beta
CRH-R-2
[ Show all ]
DiseaseN/A for non-human GPCRs
Length411
Amino acid sequenceMDAALLLSLLEANCSLALAEELLLDGWGVPPDPEGPYTYCNTTLDQIGTCWPQSAPGALVERPCPEYFNGIKYNTTRNAYRECLENGTWASRVNYSHCEPILDDKQRKYDLHYRIALIVNYLGHCVSVVALVAAFLLFLVLRSIRCLRNVIHWNLITTFILRNIAWFLLQLIDHEVHEGNEVWCRCITTIFNYFVVTNFFWMFVEGCYLHTAIVMTYSTEHLRKWLFLFIGWCIPCPIIIAWAVGKLYYENEQCWFGKEAGDLVDYIYQGPVMLVLLINFVFLFNIVRILMTKLRASTTSETIQYRKAVKATLVLLPLLGITYMLFFVNPGEDDLSQIVFIYFNSFLQSFQGFFVSVFYCFFNGEVRAALRKRWHRWQDHHALRVPVARAMSIPTSPTRISFHSIKQTAAV
UniProtQ60748
Protein Data Bank2jnd
GPCR-HGmod modelN/A
3D structure modelThis structure is from PDB ID 2jnd.
BioLiPBL0101313
Therapeutic Target DatabaseN/A
ChEMBLCHEMBL2253
IUPHAR213
DrugBankN/A

Known ligands

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Total entries: 88
Page:  / 1 

GLASS IDMoleculeFormulaMolecular weightH-bond acceptor / donorXlogPLipinski's druglikeness
12702D structureCHEMBL430078C213H348N56O61S4701.5268 / 60-16.1No
21342D structureCID 77232001C208H345N57O61S4652.4569 / 60-18.0No
81452D structureCHEMBL429069C209H347N57O62S4682.4769 / 61-18.8No
100952D structureCID 44388678C204H349N55O61S4580.4268 / 59-17.1No
114582D structureCID 44388704C208H349N55O62S4644.4669 / 60-16.8No
168442D structureCHEMBL411590C217H350N56O61S4751.5868 / 60-14.8No
190652D structureBDBM50158991C212H351N55O61S4678.5268 / 61-14.5No
200902D structureBDBM50158995C207H347N55O62S4630.4469 / 62-16.4No
225912D structureCID 44388705C201H343N55O61S4538.3468 / 59-18.5No
5224392D structureCHEMBL3774682C180H294N52O49S4002.7156 / 56-6.1No
5224482D structureCHEMBL3775437C177H290N50O493902.5754 / 55-6.6No
5224872D structureCHEMBL3774981C184H313N51O554119.8361 / 56-12.4No
396832D structureCID 77231998C210H346N58O61S4691.4869 / 61-17.9No
531182D structureCID 44388647C203H345N57O63S4624.3970 / 61-21.7No
557312D structureCID 44388723C206H345N55O63S4632.4170 / 61-18.8No
5232182D structureCHEMBL3775831C174H293N49O48S23903.6755 / 54-4.8No
654042D structureCID 44388688C205H351N55O61S4594.4568 / 59-16.8No
5234892D structureCHEMBL3774868C183H302N52O504030.7455 / 57-5.5No
700852D structureCHEMBL349500C18H13N3O2303.3214 / 02.2Yes
707292D structureCID 77231997C208H345N57O62S4668.4470 / 61-18.4No
5238222D structureCHEMBL3774594C186H298N52O494046.7555 / 56-4.6No
787872D structureBDBM50158965C207H346N56O62S4643.4469 / 62-18.2No
5239692D structureCHEMBL3774713C183H310N50O493994.7954 / 55-2.0No
898732D structureCID 44388677C204H348N56O62S4609.4269 / 60-19.2No
5243872D structureCHEMBL3775778C177H296N52O473904.6353 / 55-5.5No
1006852D structureBDBM50159003C203H347N55O62S4582.3969 / 62-17.9No
1116252D structureCHEMBL438220C213H348N56O62S4717.5269 / 61-16.4No
1124722D structureCID 44388711C208H349N55O62S4644.4669 / 60-16.8No
5249032D structureCHEMBL3775707C191H306N54O52S24255.059 / 59-5.4No
5250182D structureCHEMBL3775761C179H302N50O493938.6954 / 55-4.1No
5538902D structureAstressinC161H269N49O423563.2249 / 51-8.0No
5255262D structureCHEMBL3775030C180H294N52O49S4002.7156 / 56-6.1No
1412482D structureBDBM50158970C205H351N55O61S4594.4568 / 61-16.0No
1422672D structureCID 44388680C215H349N55O61S4712.5468 / 59-15.0No
1454072D structureCID 44388679C211H347N55O61S4662.4868 / 59-16.2No
1521662D structureCID 44388608C203H347N55O62S4582.3969 / 60-18.7No
1584562D structureBDBM50158961C208H349N55O61S4628.4668 / 61-15.7No
1590392D structureCID 44388623C208H349N55O61S4628.4668 / 59-16.5No
1620532D structureBDBM50158969C205H351N55O61S4594.4568 / 61-16.0No
1679622D structureBDBM50158974C205H343N55O61S4586.3868 / 61-17.1No
1681152D structureBDBM50158983C202H345N55O64S4600.3671 / 64-19.2No
5263972D structureCHEMBL3774742C172H288N50O493840.554 / 55-7.7No
5266642D structureCHEMBL3774485C177H295N51O483905.6254 / 55-4.8No
1829772D structureBDBM50158998C204H347N55O63S4610.470 / 62-17.8No
1842162D structureBDBM50158968C211H348N56O62S4693.569 / 62-17.0No
1861702D structureCID 44388638C205H343N55O62S4602.3869 / 60-18.2No
1935262D structureBDBM50158962C204H348N56O62S4609.4269 / 62-18.5No
2050902D structureCID 44388710C211H347N55O62S4678.4869 / 60-16.6No
2063902D structureCID 44388681C207H347N55O61S4614.4468 / 59-16.8No
2067602D structureBDBM50158986C206H345N55O63S4632.4170 / 63-18.0No
2090522D structureCID 44388685C206H344N56O63S4645.4170 / 61-19.7No
2187172D structure7-Oxo-7H-benzo[e]perimidine-4-carboxylic acidC16H8N2O3276.2515 / 12.2Yes
2333442D structureCHEMBL429547C210H350N56O61S4667.568 / 60-16.4No
2571182D structureBDBM50158979C215H349N55O62S4728.5469 / 62-14.6No
2591922D structureCID 77231999C212H347N57O61S4702.5169 / 60-16.8No
2608712D structureCID 44388659C183H323N57O524153.9458 / 58-10.2No
2641482D structureUNII-D8690V3244C208H343N59O64S24758.573 / 67-13.6No
2778402D structureCID 44388687C205H351N55O61S4594.4568 / 59-16.8No
5302472D structureCHEMBL3775830C171H282N52O493850.4555 / 56-9.0No
3112232D structureCHEMBL410347C210H350N56O61S4667.568 / 60-16.4No
5305322D structureCHEMBL3775192C174H292N50O493868.5554 / 55-6.8No
3206612D structureCHEMBL161962C18H14N4O2318.3365 / 21.1Yes
5305942D structureCHEMBL3774939C171H286N50O493826.4754 / 55-8.2No
5306102D structureCHEMBL3774465C173H290N50O493854.5254 / 55-7.4No
5309552D structureCHEMBL3775678C173H286N52O493878.5155 / 56-8.6No
3367312D structureBDBM50158996C204H348N56O62S4609.4269 / 62-18.5No
5311322D structureCHEMBL3774836C175H294N50O493882.5854 / 55-6.3No
5311472D structureCHEMBL3774395C175H294N50O493882.5854 / 55-6.3No
5312962D structureCHEMBL3775621C182H296N52O493996.6955 / 56-5.8No
3564892D structureCID 44388696C207H346N56O63S4659.4370 / 61-19.3No
3641412D structureBDBM50158957C208H349N55O62S4644.4669 / 62-16.1No
5686932D structureCHEMBL164829C20H18N6O2374.4047 / 40.4Yes
3671142D structureCHEMBL414568C208H346N56O62S4655.4569 / 61-18.3No
3691052D structureBDBM50159004C206H345N55O62S4616.4169 / 62-17.7No
5688702D structureCHEMBL352154C24H24N6O2428.4967 / 41.7Yes
5688732D structureCHEMBL164931C24H24N6O2428.4967 / 41.7Yes
3849272D structureBDBM50158992C207H346N56O62S4643.4469 / 62-18.2No
5692572D structureCHEMBL168162C28H30N6O2482.5887 / 43.1Yes
3879472D structureCID 77232002C205H347N57O61S4618.4369 / 60-18.3No
3887402D structureCID 77232000C204H344N58O62S4633.470 / 61-20.8No
3891812D structureBDBM50158993C204H348N56O62S4609.4269 / 62-18.5No
4038212D structureBDBM50158975C209H345N55O61S4636.4468 / 61-15.8No
4041902D structureCID 44388720C211H347N55O63S4694.4870 / 61-16.9No
5329472D structureCHEMBL3775812C186H298N52O494046.7555 / 56-4.6No
5330402D structureCHEMBL3775796C179H298N52O493962.6755 / 56-6.0No
4081182D structureCHEMBL350784C22H20N4O2372.4285 / 22.4Yes
4081202D structureCHEMBL352131C22H20N4O2372.4285 / 22.4Yes
4342252D structureBDBM50158966C207H346N56O63S4659.4370 / 63-18.6No

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