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BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

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GPCR

Name5-hydroxytryptamine receptor 2C
SpeciesCanis lupus familiaris (Dog)
GeneHTR2C
Synonym5-HT-2C
5-HT2C
5-HTR2C
Serotonin receptor 2C
DiseaseN/A for non-human GPCRs
Length458
Amino acid sequenceMVNLRKAVHSFLVHLIGLLVWQCDISVSPVAALVTDIFNTSDGGRFKFPDGVQNWPALSIVIIIILTIGGNILVIMAVSLEKKLHNATNYFLMSLAIADMLVGLLVMPLSLLAILYDYVWPLPRYLCPVWISLDVLFSTASIMHLCAISLDRYVAIRNPVEHSRFNSRTKAIMKIAIVWAISIGVSVPIPVIGLRDEEKVFVNNTTCVLNDPNFVLIGSFVAFFIPLTIMVITYCLTIHVLRRQALMLLHGHVEEPPRINLDFLKCCRRNGTEEENSANPNQDSNPRRRKKKERRPRGTMQAINNERKASKVLGIVFFVFLVMWCPFFITNILSVLCGKACNQKLMEKLLNVFVWIGYVCSGINPLVYTLFNKIYRRAFSNYLRCNYKPEKKPPVRQMPRVAATALSGRELNVNIYRHTNEPVLKKANDKEPGIEMQVENLELPVNPSSVVSERISSV
UniProtQ60F97
Protein Data BankN/A
GPCR-HGmod modelN/A
3D structure modelNo available structures or models
BioLiPN/A
Therapeutic Target DatabaseN/A
ChEMBLCHEMBL1770041
IUPHARN/A
DrugBankN/A

Known ligands

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Total entries: 4
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GLASS IDMoleculeFormulaMolecular weightH-bond acceptor / donorXlogPLipinski's druglikeness
547352D structure2-benzyl-6,7,8,9-tetrahydro-5H-pyrimido[4,5-d]azepineC15H17N3239.3223 / 12.1Yes
838882D structureKetanserinC22H22FN3O3395.4345 / 12.6Yes
3349932D structure(S)-mianserinC18H20N2264.3722 / 03.4Yes
4007132D structureLorcaserinC11H14ClN195.691 / 12.7Yes

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