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| Name | Prostaglandin E2 receptor EP2 subtype |
|---|---|
| Species | Mus musculus (Mouse) |
| Gene | Ptger2 |
| Synonym | EP2 receptor PGE receptor EP2 subtype PGE2 receptor EP2 subtype prostaglandin E receptor 2 (subtype EP2), 53kDa prostanoid EP2 receptor [ Show all ] |
| Disease | N/A for non-human GPCRs |
| Length | 362 |
| Amino acid sequence | MDNFLNDSKLMEDCKSRQWLLSGESPAISSVMFSAGVLGNLIALALLARRWRGDTGCSAGSRTSISLFHVLVTELVLTDLLGTCLISPVVLASYSRNQTLVALAPESHACTYFAFTMTFFSLATMLMLFAMALERYLSIGYPYFYRRHLSRRGGLAVLPVIYGASLLFCSLPLLNYGEYVQYCPGTWCFIRHGRTAYLQLYATMLLLLIVAVLACNISVILNLIRMHRRSRRSRCGLSGSSLRGPGSRRRGERTSMAEETDHLILLAIMTITFAICSLPFTIFAYMDETSSLKEKWDLRALRFLSVNSIIDPWVFAILRPPVLRLMRSVLCCRTSLRTQEAQQTSCSTQSSASKQTDLCGQL |
| UniProt | Q62053 |
| Protein Data Bank | N/A |
| GPCR-HGmod model | N/A |
| 3D structure model | No available structures or models |
| BioLiP | N/A |
| Therapeutic Target Database | N/A |
| ChEMBL | CHEMBL2488 |
| IUPHAR | 341 |
| DrugBank | N/A |
You can:
| GLASS ID | Molecule | Formula | Molecular weight | H-bond acceptor / donor | XlogP | Lipinski's druglikeness |
|---|---|---|---|---|---|---|
| 3025 |  CHEMBL1929538 | C21H29NO6S | 423.524 | 7 / 2 | 1.7 | Yes |
| 7816 |  CHEMBL1929550 | C23H33NO4S | 419.58 | 5 / 2 | 2.8 | Yes |
| 8331 |  CHEMBL1094419 | C30H35NO4 | 473.613 | 4 / 2 | 6.4 | No |
| 8335 |  CHEMBL596956 | C30H35NO4 | 473.613 | 4 / 2 | 6.4 | No |
| 9982 |  CHEMBL1094160 | C30H33F2NO4 | 509.594 | 6 / 2 | 6.6 | No |
| 11640 |  AH 6809 | C17H14O5 | 298.294 | 5 / 1 | 3.9 | Yes |
| 553316 |  Cicaprost | C22H30O5 | 374.477 | 5 / 3 | 2.1 | Yes |
| 12773 |  CID 53394056 | C22H30O5 | 374.477 | 5 / 3 | 2.1 | Yes |
| 13146 |  CHEMBL1929526 | C23H33NO5 | 403.519 | 5 / 2 | 2.2 | Yes |
| 15945 |  CHEMBL2315052 | C24H23Cl2FN2O2 | 461.358 | 4 / 0 | 6.2 | No |
| 17795 |  CHEMBL2315053 | C27H25Cl2FN2O2 | 499.407 | 4 / 1 | 7.0 | No |
| 18600 |  CHEMBL305126 | C21H28O6S2 | 440.569 | 8 / 3 | 2.3 | Yes |
| 19265 |  acrylic acid derivative, 4 | C25H22N2O3 | 398.462 | 4 / 1 | 5.0 | Yes |
| 19498 |  CHEMBL2037291 | C29H29N3O5S2 | 563.687 | 9 / 2 | 5.1 | No |
| 20623 |  CHEMBL186735 | C26H23NO5 | 429.472 | 5 / 1 | 5.0 | Yes |
| 23627 |  CHEMBL595830 | C25H24N2O4 | 416.477 | 5 / 1 | 4.3 | Yes |
| 465995 |  CHEMBL3586309 | C24H22N2O2S | 402.512 | 5 / 0 | 4.5 | Yes |
| 25483 |  CHEMBL1819607 | C27H28N2O5 | 460.53 | 6 / 1 | 4.4 | Yes |
| 30049 |  CHEMBL2315056 | C26H17Cl4FN2O4S | 614.29 | 6 / 1 | 7.6 | No |
| 31708 |  CHEMBL1095117 | C29H31F2NO4 | 495.567 | 6 / 2 | 6.6 | No |
| 553422 |  ONO-AE1-329 | C23H32O6S2 | 468.623 | 8 / 3 | 2.3 | Yes |
| 35053 |  CHEMBL1819611 | C27H28N2O5 | 460.53 | 6 / 2 | 4.5 | Yes |
| 35477 |  CHEMBL303532 | C24H34O6S2 | 482.65 | 8 / 3 | 2.8 | Yes |
| 36791 |  CHEMBL591034 | C25H25NO4 | 403.478 | 4 / 2 | 4.4 | Yes |
| 38363 |  CHEMBL1091741 | C31H27F2N3O4S | 575.631 | 7 / 1 | 5.8 | No |
| 40197 |  CHEMBL1929527 | C22H31NO5S | 421.552 | 6 / 2 | 1.6 | Yes |
| 41352 |  indomethacin | C19H16ClNO4 | 357.79 | 4 / 1 | 4.3 | Yes |
| 41632 |  CHEMBL62885 | C24H38O5 | 406.563 | 5 / 3 | 4.1 | Yes |
| 42118 |  CHEMBL364421 | C23H25NO5 | 395.455 | 5 / 1 | 4.9 | Yes |
| 44627 |  CHEMBL1813120 | C29H28N2O5 | 484.552 | 6 / 1 | 5.4 | No |
| 46084 |  CHEMBL1929545 | C21H29NO3S | 375.527 | 4 / 2 | 3.1 | Yes |
| 46524 |  CHEMBL2036325 | C27H24ClN3O4S3 | 586.136 | 9 / 2 | 5.6 | No |
| 49034 |  CHEMBL1929539 | C19H25NO4S2 | 395.532 | 6 / 2 | 2.6 | Yes |
| 51162 |  CHEMBL1091743 | C30H26F2N4O4S | 576.619 | 8 / 2 | 5.1 | No |
| 51200 |  CHEMBL595159 | C25H20N2O3 | 396.446 | 4 / 1 | 5.1 | No |
| 52449 |  CHEMBL60555 | C19H32O5S | 372.52 | 6 / 3 | 2.2 | Yes |
| 53538 |  CHEMBL1095769 | C32H39NO4 | 501.667 | 4 / 2 | 7.1 | No |
| 54265 |  CHEMBL1094813 | C32H39NO4 | 501.667 | 4 / 2 | 7.1 | No |
| 55826 |  CHEMBL1929528 | C23H32O5S | 420.564 | 6 / 2 | 2.5 | Yes |
| 61112 |  acrylic acid derivative, 9 | C22H22N2O4 | 378.428 | 5 / 1 | 3.6 | Yes |
| 553581 |  Doproston | C20H34O4 | 338.488 | 4 / 2 | 4.2 | Yes |
| 65787 |  11-deoxy Prostaglandin E1 | C20H34O4 | 338.488 | 4 / 2 | 4.2 | Yes |
| 70665 |  CHEMBL2036319 | C27H28N2O5S2 | 524.65 | 8 / 2 | 4.5 | No |
| 73357 |  CHEMBL1813115 | C28H26N2O5 | 470.525 | 6 / 1 | 5.0 | Yes |
| 553641 |  Rivenprost | C24H34O6S | 450.59 | 7 / 2 | 1.8 | Yes |
| 76212 |  CHEMBL1819606 | C26H26N2O5 | 446.503 | 6 / 1 | 4.0 | Yes |
| 76899 |  CHEMBL361098 | C22H23NO5 | 381.428 | 5 / 1 | 4.7 | Yes |
| 77516 |  acrylic acid derivative, 6 | C24H28O5 | 396.483 | 5 / 2 | 5.2 | No |
| 78139 |  CHEMBL1813117 | C28H25ClN2O5 | 504.967 | 6 / 1 | 5.9 | No |
| 79307 |  CHEMBL292717 | C24H34O6S2 | 482.65 | 8 / 3 | 2.9 | Yes |
| 79336 |  CHEMBL1957434 | C22H24ClNO4S | 433.947 | 5 / 2 | 4.0 | Yes |
| 88525 |  CHEMBL62888 | C21H28O6S2 | 440.569 | 8 / 3 | 2.3 | Yes |
| 91018 |  CHEMBL1957436 | C26H25ClN2O4S2 | 529.066 | 7 / 2 | 5.1 | No |
| 94338 |  CHEMBL62868 | C19H32O5S | 372.52 | 6 / 3 | 2.2 | Yes |
| 96075 |  CHEMBL1933718 | C24H27NO4 | 393.483 | 4 / 2 | 3.3 | Yes |
| 96938 |  CHEMBL1094814 | C29H34N2O4 | 474.601 | 5 / 2 | 5.3 | No |
| 97554 |  CHEMBL2037292 | C27H24ClN3O5S2 | 570.075 | 9 / 2 | 5.0 | No |
| 98918 |  CHEMBL183933 | C23H25NO4 | 379.456 | 4 / 1 | 5.3 | No |
| 100249 |  15(R)-Prostaglandin E1 | C20H34O5 | 354.487 | 5 / 3 | 3.2 | Yes |
| 100251 |  alprostadil | C20H34O5 | 354.487 | 5 / 3 | 3.2 | Yes |
| 107366 |  CHEMBL365829 | C28H25NO5 | 455.51 | 5 / 1 | 5.5 | No |
| 114990 |  acrylic acid derivative, 16 | C28H24O4 | 424.496 | 4 / 1 | 6.5 | No |
| 115627 |  ILOPROST | C22H32O4 | 360.494 | 4 / 3 | 2.8 | Yes |
| 553848 |  ILOPROST | C22H32O4 | 360.494 | 4 / 3 | 2.8 | Yes |
| 116633 |  UNII-CQ5912425U | C20H14Cl2FNO3 | 406.234 | 5 / 1 | 5.5 | No |
| 116851 |  CHEMBL293242 | C23H36O5 | 392.536 | 5 / 3 | 3.6 | Yes |
| 116855 |  CHEMBL294585 | C23H36O5 | 392.536 | 5 / 3 | 3.6 | Yes |
| 120656 |  CHEMBL293856 | C22H30O6S2 | 454.596 | 8 / 3 | 2.0 | Yes |
| 122778 |  CHEMBL602337 | C28H31NO4 | 445.559 | 4 / 2 | 5.6 | No |
| 122819 |  CHEMBL182555 | C22H23NO4 | 365.429 | 4 / 1 | 4.6 | Yes |
| 124614 |  CHEMBL2036314 | C28H31NO5S | 493.618 | 6 / 2 | 4.0 | Yes |
| 127543 |  CHEMBL64188 | C19H32O5S | 372.52 | 6 / 3 | 2.7 | Yes |
| 127761 |  CHEMBL62779 | C23H32O6S2 | 468.623 | 8 / 3 | 2.4 | Yes |
| 132800 |  CHEMBL439934 | C24H33FO5 | 420.521 | 6 / 3 | 3.0 | Yes |
| 134267 |  CHEMBL1813118 | C28H25FN2O5 | 488.515 | 7 / 1 | 5.4 | No |
| 136108 |  CHEMBL1929542 | C20H24F3NO4S2 | 463.53 | 9 / 2 | 3.5 | Yes |
| 139555 |  CHEMBL64483 | C22H34O5 | 378.509 | 5 / 3 | 3.0 | Yes |
| 140014 |  CHEMBL1929531 | C21H29NO5S | 407.525 | 6 / 2 | 2.9 | Yes |
| 143370 |  CHEMBL64217 | C18H30O5S2 | 390.553 | 7 / 3 | 2.7 | Yes |
| 143428 |  acrylic acid derivative, 12 | C25H22N2O3 | 398.462 | 4 / 1 | 4.7 | Yes |
| 143856 |  CHEMBL64187 | C19H32O5S | 372.52 | 6 / 3 | 2.2 | Yes |
| 143924 |  acrylic acid derivative, 17 | C28H24O4 | 424.496 | 4 / 1 | 6.5 | No |
| 145303 |  CHEMBL64072 | C23H33FO5S | 440.57 | 7 / 3 | 2.8 | Yes |
| 145869 |  SCHEMBL2962411 | C23H21Cl2FN2O4S | 511.389 | 6 / 1 | 5.7 | No |
| 146094 |  99946-24-4 | C21H34O4 | 350.499 | 4 / 3 | 3.4 | Yes |
| 554007 |  Isocarbacyclin | C21H34O4 | 350.499 | 4 / 3 | 3.4 | Yes |
| 147469 |  CHEMBL2036326 | C28H27N3O5S2 | 549.66 | 9 / 2 | 4.7 | No |
| 481141 |  4-(7-(5-Fluoro-1H-indole-1-yl)-9-chloro-2,3,4,5-tetrahydro-1,4-benzooxazepine-4-yl)methylpyridine-2(1H)-one | C23H19ClFN3O2 | 423.872 | 4 / 1 | 3.3 | Yes |
| 148126 |  CHEMBL222715 | C21H29NO4 | 359.466 | 4 / 2 | 3.3 | Yes |
| 148343 |  CHEMBL185277 | C26H31NO5 | 437.536 | 5 / 1 | 6.1 | No |
| 152588 |  CHEMBL1933723 | C21H24N2O4S2 | 432.553 | 7 / 2 | 3.2 | Yes |
| 154145 |  CHEMBL361457 | C26H23NO4 | 413.473 | 4 / 1 | 5.3 | No |
| 154223 |  CHEMBL1933726 | C23H25F3N2O5S2 | 530.577 | 11 / 2 | 3.6 | No |
| 154458 |  CHEMBL1813116 | C29H28N2O5 | 484.552 | 6 / 1 | 5.4 | No |
| 158724 |  CHEMBL2036315 | C26H32N2O5S | 484.611 | 7 / 2 | 2.3 | Yes |
| 158752 |  CHEMBL2315050 | C24H23Cl2FN2O2 | 461.358 | 4 / 1 | 6.6 | No |
| 158908 |  CHEMBL1929533 | C20H24F3NO5S | 447.469 | 9 / 2 | 2.9 | Yes |
| 160115 |  CHEMBL2037289 | C28H27N3O5S2 | 549.66 | 9 / 2 | 4.7 | No |
| 160672 |  CHEMBL603633 | C24H22N2O4 | 402.45 | 5 / 1 | 4.6 | Yes |
| 163570 |  CHEMBL2036312 | C27H30N2O5S | 494.606 | 7 / 2 | 3.4 | Yes |
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