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| Name | Glucose-dependent insulinotropic receptor |
|---|---|
| Species | Mus musculus (Mouse) |
| Gene | Gpr119 |
| Synonym | G protein-coupled receptor 119 G-protein coupled receptor 119 G-protein coupled receptor 2 glucose-dependent insulinotropic receptor GPCR2 [ Show all ] |
| Disease | N/A for non-human GPCRs |
| Length | 335 |
| Amino acid sequence | MESSFSFGVILAVLTILIIAVNALVVVAMLLSIYKNDGVGLCFTLNLAVADTLIGVAISGLVTDQLSSSAQHTQKTLCSLRMAFVTSSAAASVLTVMLIAFDRYLAIKQPLRYFQIMNGLVAGACIAGLWLVSYLIGFLPLGVSIFQQTTYHGPCSFFAVFHPRFVLTLSCAGFFPAVLLFVFFYCDMLKIASVHSQQIRKMEHAGAMAGAYRPPRSVNDFKAVRTIAVLIGSFTLSWSPFLITSIVQVACHKCCLYQVLEKYLWLLGVGNSLLNPLIYAYWQREVRQQLYHMALGVKKFFTSILLLLPARNRGPERTRESAYHIVTISHPELDG |
| UniProt | Q7TQP3 |
| Protein Data Bank | N/A |
| GPCR-HGmod model | N/A |
| 3D structure model | No available structures or models |
| BioLiP | N/A |
| Therapeutic Target Database | N/A |
| ChEMBL | CHEMBL5263 |
| IUPHAR | N/A |
| DrugBank | N/A |
You can:
| GLASS ID | Molecule | Formula | Molecular weight | H-bond acceptor / donor | XlogP | Lipinski's druglikeness |
|---|---|---|---|---|---|---|
| 152 |  CHEMBL2058674 | C22H30N4O2 | 382.508 | 6 / 1 | 4.6 | Yes |
| 8885 |  CHEMBL2086689 | C20H19FN8O | 406.425 | 10 / 0 | 1.5 | Yes |
| 442066 |  CHEMBL3354776 | C26H24F3N3O2 | 467.492 | 7 / 0 | 5.8 | No |
| 442143 |  CHEMBL3358010 | C23H26F4N4O6S | 562.537 | 13 / 0 | 2.1 | No |
| 442150 |  CHEMBL3354805 | C25H21F4N5O | 483.471 | 9 / 2 | 2.6 | Yes |
| 12678 |  CID 62707005 | C21H28N4O2S | 400.541 | 7 / 1 | 5.1 | No |
| 442258 |  CHEMBL3358000 | C20H18F4N10O2 | 506.426 | 15 / 0 | 2.6 | No |
| 16558 |  CHEMBL2086686 | C21H23N7O3 | 421.461 | 9 / 0 | 1.3 | Yes |
| 18441 |  CHEMBL2010836 | C23H25F3N6O | 458.489 | 8 / 0 | 3.6 | Yes |
| 18612 |  CHEMBL1771084 | C21H28N4O2S | 400.541 | 6 / 0 | 2.8 | Yes |
| 20783 |  CHEMBL3220233 | C22H24N8O4 | 464.486 | 12 / 0 | 0.7 | No |
| 22028 |  CHEMBL1777817 | C22H28N4O4 | 412.49 | 7 / 0 | 3.9 | Yes |
| 442585 |  CHEMBL3354781 | C27H24F3N3O2 | 479.503 | 7 / 0 | 5.8 | No |
| 24577 |  CHEMBL1778247 | C22H24FN5O3S | 457.524 | 9 / 1 | 3.6 | Yes |
| 25011 |  CHEMBL2382408 | C23H30N4O5S | 474.576 | 8 / 0 | 2.6 | Yes |
| 466243 |  CHEMBL3622172 | C23H30FN3O4S | 463.568 | 8 / 0 | 2.4 | Yes |
| 522436 |  n-oleoylethanolamine | C20H39NO2 | 325.537 | 2 / 2 | 6.3 | No |
| 467381 |  CHEMBL3629479 | C24H31ClN4O6S | 539.044 | 9 / 1 | 3.8 | No |
| 38027 |  CHEMBL2086655 | C22H29N3O5S | 447.55 | 7 / 0 | 2.7 | Yes |
| 443235 |  CHEMBL3358004 | C21H23F4N7O3S | 529.515 | 14 / 1 | 3.8 | No |
| 443463 |  CHEMBL3358007 | C21H22F4N6O3S | 514.5 | 14 / 0 | 2.8 | No |
| 45634 |  CHEMBL1771098 | C24H28ClFN4O2 | 458.962 | 6 / 1 | 4.8 | Yes |
| 48063 |  CHEMBL1771088 | C22H28ClN3O2S | 433.995 | 5 / 0 | 4.5 | Yes |
| 48501 |  CHEMBL1771093 | C20H24ClN7 | 397.911 | 7 / 0 | 3.7 | Yes |
| 49272 |  CHEMBL1770918 | C20H31N3O2 | 345.487 | 4 / 0 | 3.4 | Yes |
| 468994 |  CHEMBL3622177 | C24H32FN3O4S | 477.595 | 8 / 0 | 2.8 | Yes |
| 469388 |  CHEMBL3622167 | C22H30FN3O4S | 451.557 | 8 / 0 | 3.8 | Yes |
| 443815 |  CHEMBL3354790 | C24H18F3N3O3 | 453.421 | 8 / 0 | 4.0 | Yes |
| 53719 |  CHEMBL2058391 | C21H32N2O4S | 408.557 | 5 / 1 | 3.5 | Yes |
| 55498 |  CHEMBL2086658 | C22H29N3O5S | 447.55 | 7 / 0 | 2.4 | Yes |
| 57442 |  CHEMBL1771065 | C22H34N2O2 | 358.526 | 3 / 0 | 4.8 | Yes |
| 57572 |  CHEMBL3220238 | C23H28N6O4 | 452.515 | 9 / 0 | 1.7 | Yes |
| 57741 |  CHEMBL1778150 | C21H26N4O4S | 430.523 | 8 / 0 | 3.1 | Yes |
| 58350 |  CHEMBL2382412 | C21H20F4N6O3 | 480.424 | 12 / 0 | 2.4 | No |
| 58564 |  CHEMBL2058397 | C19H30N4O4S | 410.533 | 7 / 3 | 3.2 | Yes |
| 59098 |  733750-99-7 | C21H24FN7O5S | 505.525 | 12 / 1 | 3.9 | No |
| 60427 |  CHEMBL1771083 | C22H29N3O2S | 399.553 | 5 / 0 | 3.9 | Yes |
| 444129 |  CHEMBL3357999 | C20H17F4N7O2 | 463.397 | 13 / 0 | 3.1 | No |
| 470699 |  CHEMBL3629597 | C24H26FN5O5 | 483.5 | 10 / 1 | 2.8 | Yes |
| 63342 |  CHEMBL2058673 | C23H30N4O | 378.52 | 5 / 1 | 4.3 | Yes |
| 65150 |  CHEMBL1771069 | C22H34N2O4S | 422.584 | 5 / 0 | 3.7 | Yes |
| 73030 |  CID 62706519 | C21H30N2O4 | 374.481 | 5 / 1 | 3.8 | Yes |
| 75849 |  CHEMBL1778145 | C24H30N4O4 | 438.528 | 7 / 0 | 4.3 | Yes |
| 80021 |  CHEMBL1771064 | C21H32N2O2 | 344.499 | 3 / 0 | 4.4 | Yes |
| 83749 |  CHEMBL1778151 | C21H28N4O4S | 432.539 | 8 / 0 | 3.4 | Yes |
| 91322 |  CHEMBL2087084 | C21H24N8O2 | 420.477 | 10 / 0 | 2.5 | Yes |
| 93778 |  CHEMBL2058405 | C22H32N2O4 | 388.508 | 5 / 1 | 3.7 | Yes |
| 95357 |  SCHEMBL1447845 | C21H21F3N6O4 | 478.432 | 12 / 0 | 1.5 | No |
| 445519 |  CHEMBL3358012 | C22H24F4N4O6S | 548.51 | 13 / 0 | 2.2 | No |
| 445609 |  CHEMBL3354804 | C26H22F4N4O | 482.483 | 8 / 2 | 3.6 | Yes |
| 101590 |  CHEMBL1771095 | C21H27N7 | 377.496 | 7 / 0 | 3.0 | Yes |
| 103368 |  CHEMBL2086668 | C21H35N5O5S | 469.601 | 9 / 0 | 1.8 | Yes |
| 108420 |  CHEMBL2086675 | C19H25N5O3 | 371.441 | 7 / 0 | 1.7 | Yes |
| 446099 |  CHEMBL3358014 | C22H27FN6O4S | 490.554 | 11 / 0 | 3.2 | No |
| 112393 |  CHEMBL2058398 | C22H32N2O3 | 372.509 | 4 / 1 | 4.0 | Yes |
| 446187 |  CHEMBL3358013 | C23H29FN6O4S | 504.581 | 11 / 0 | 3.1 | No |
| 114668 |  CHEMBL1771099 | C24H28ClFN4O2 | 458.962 | 6 / 1 | 4.8 | Yes |
| 116932 |  CHEMBL2086666 | C22H28N4O5S | 460.549 | 8 / 0 | 2.3 | Yes |
| 477440 |  CHEMBL3622174 | C23H30FN3O3S | 447.569 | 7 / 0 | 3.5 | Yes |
| 123490 |  CHEMBL3220240 | C21H24N6O4 | 424.461 | 9 / 0 | 0.8 | Yes |
| 125734 |  CHEMBL2382410 | C22H26N6O3 | 422.489 | 8 / 0 | 2.1 | Yes |
| 446649 |  CHEMBL3358006 | C21H22F4N6O4S | 530.499 | 14 / 0 | 2.9 | No |
| 446819 |  CHEMBL3354780 | C25H19F4N3O2 | 469.44 | 8 / 0 | 5.0 | Yes |
| 446831 |  CHEMBL3357998 | C21H23F3N6O4S | 512.508 | 13 / 0 | 2.4 | No |
| 137689 |  CHEMBL3260506 | C23H18Cl2FN3O2 | 458.314 | 5 / 0 | 5.5 | No |
| 138746 |  CHEMBL2086693 | C19H17F3N8O2 | 446.394 | 13 / 0 | 2.3 | No |
| 140541 |  CID 62706851 | C22H26N4O4 | 410.474 | 8 / 1 | 3.2 | Yes |
| 141845 |  CHEMBL2086650 | C21H28N4O5S | 448.538 | 8 / 0 | 2.0 | Yes |
| 447379 |  CHEMBL3358001 | C21H22F4N6O4S | 530.499 | 14 / 0 | 2.5 | No |
| 145877 |  CHEMBL3217767 | C21H24N8O2 | 420.477 | 10 / 0 | 2.1 | Yes |
| 148633 |  CHEMBL1778144 | C23H28N4O4 | 424.501 | 7 / 0 | 3.9 | Yes |
| 148983 |  CHEMBL1778253 | C21H25FN4O4S | 448.513 | 9 / 0 | 3.1 | Yes |
| 149084 |  CHEMBL1778152 | C21H25F3N4O4S | 486.51 | 11 / 0 | 4.0 | No |
| 153456 |  CHEMBL1778239 | C24H25FN4O4S | 484.546 | 9 / 0 | 4.2 | Yes |
| 481907 |  CHEMBL3629596 | C23H24ClN5O4 | 469.926 | 8 / 1 | 3.4 | Yes |
| 154508 |  CHEMBL2086685 | C20H24N6O3 | 396.451 | 8 / 0 | 1.7 | Yes |
| 154802 |  CHEMBL3220244 | C20H22N6O4 | 410.434 | 9 / 0 | 0.6 | Yes |
| 156054 |  compound 36j | C22H24ClN5O3S | 473.976 | 8 / 1 | 4.1 | Yes |
| 157239 |  CID 62706850 | C21H26N4O3 | 382.464 | 7 / 1 | 3.3 | Yes |
| 157496 |  BDBM50387903 | C21H30N2O4 | 374.481 | 5 / 2 | 4.3 | Yes |
| 160221 |  CHEMBL2087085 | C21H22N8O2 | 418.461 | 10 / 0 | 1.9 | Yes |
| 160865 |  CHEMBL2087086 | C19H17F3N8O2 | 446.394 | 13 / 0 | 2.3 | No |
| 482853 |  CHEMBL3629598 | C22H24ClN5O4S | 489.975 | 9 / 1 | 3.2 | Yes |
| 162369 |  CHEMBL2086677 | C20H27N5O3 | 385.468 | 7 / 0 | 2.1 | Yes |
| 165911 |  CHEMBL1778251 | C21H24N4O4S | 428.507 | 8 / 0 | 2.8 | Yes |
| 165965 |  CHEMBL1778241 | C21H24ClN3O4S | 449.95 | 7 / 0 | 4.4 | Yes |
| 166618 |  CHEMBL3260540 | C24H21F3N4O2 | 454.453 | 8 / 0 | 4.4 | Yes |
| 166705 |  SCHEMBL1447914 | C22H24N8O3 | 448.487 | 11 / 0 | 1.6 | No |
| 168541 |  CHEMBL2086672 | C22H29FN4O5S | 480.555 | 9 / 0 | 2.6 | Yes |
| 448445 |  CHEMBL3354803 | C25H19F4N5O3 | 513.453 | 10 / 2 | 3.0 | No |
| 484311 |  2-(4-((1R,2R)-2-(((2-fluoro-4-(methylsulfonyl)benzyl)oxy)methyl)cyclopropyl)piperidin-1-yl)-5-(methoxymethyl)pyrimidine | C23H30FN3O4S | 463.568 | 8 / 0 | 2.4 | Yes |
| 173250 |  CHEMBL1771081 | C21H31N5O2 | 385.512 | 6 / 0 | 3.5 | Yes |
| 173473 |  CHEMBL2086679 | C19H24FN5O3 | 389.431 | 8 / 0 | 1.8 | Yes |
| 485105 |  CHEMBL3629478 | C24H28ClN5O4 | 485.969 | 8 / 1 | 4.3 | Yes |
| 448764 |  CHEMBL3354774 | C26H24F3N3O2 | 467.492 | 7 / 0 | 5.7 | No |
| 485223 |  CHEMBL3622169 | C22H28FN5O3 | 429.496 | 7 / 0 | 3.0 | Yes |
| 186269 |  CHEMBL2058406 | C21H31N3O3 | 373.497 | 4 / 2 | 3.1 | Yes |
| 191058 |  CHEMBL2086659 | C22H30N4O5S | 462.565 | 8 / 0 | 2.5 | Yes |
| 191061 |  CHEMBL2086660 | C22H30N4O5S | 462.565 | 8 / 0 | 2.5 | Yes |
| 191971 |  CHEMBL1771103 | C21H26N6O | 378.48 | 7 / 0 | 3.7 | Yes |
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