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GPCR

Name	G-protein coupled receptor family C group 6 member A
Species	Mus musculus (Mouse)
Gene	Gprc6a
Synonym	G protein-coupled receptor G protein-coupled receptor, class C, group 6, member A G protein-coupled receptor, family C, group 6, member A GPCR6A GPRC6 receptor
Disease	N/A for non-human GPCRs
Length	928
Amino acid sequence	MALLITVVTCFMIILDTSQSCHTPDDFVAITSPGHIMIGGLFAIHEKMLSSDDHPRRPQIQKCAGFEISVFLQTLAMIHSIEMINNSTLLSGVKLGYEIYDTCTEVTAAMAATLRFLSKFNCSRETVVFQCDYSSYMPRVKAVIGAGYSETSIAVSRMLNLQLMPQVSYESTAEILSDKIRFPSFLRTVPSDFYQTKAMAHLIRQSGWNWIGAITTDDDYGRLALNTFAIQAAENNVCIAFKEVLPAFLSDNTIEVRINQTLEKIIAEAQVNVIVVFLRKFHVFNLFTKAIERKISKIWIASDNWSTATKIITIPNVKKLGKVVGFAFRRGNTSSFHSFLQTLHMYPNDNNKPLHEFAMLVSACKYIKDGDLSQCISNYSQATLTYDTTKTIENHLFKRNDFLWHYTEPGLIYSIQLAVFALGHAIRDLCQARDCKKPNAFQPWELLAVLKNVTFTDGRNSFHFDAHGDLNTGYDVVLWKETNGLMTVTKMAEYDLQRDVFITTNQETKHEFRKLKQILSKCSKECSPGQMKKATGSQHSCCYECVSCPENHYSNETDMDHCLLCNNETHWAPVRSTTCFEKEVEYLDWDDSLALLLIALSLLGIAFVLAIGIIFTRNLKTPVVKSSGGLVVCYVMLICHALNFASTGFFIGEPQDFACKTRQTLFGVSFTLCVSCILTKSLKILLAFSFDPKLTMFLKCLYRPVPIVLTCTGIQVVICTLWLVLAAPSVEENISLPRVIILECEEGSALAFGTMLGYITVLAFICFVFAFKGRKLPENYNEAKFLTFGMLIYFIAWITFIPVYTTTFGKYLPAVEIIVILISNYGILCCIFFPKCYIILCKQKTNTKSAFLQMVYNYSAHSVDSLALSHVSLDSTSYDTATTNQSPGNKMTACQNDNHLPAQVLPHTGTAKTIKASKTLRQKRSSSI
UniProt	Q8K4Z6
Protein Data Bank	N/A
GPCR-HGmod model	N/A
3D structure model	No available structures or models
BioLiP	N/A
Therapeutic Target Database	N/A
ChEMBL	CHEMBL3347255
IUPHAR	55
DrugBank	N/A

Known ligands

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GLASS ID	Molecule	Formula	Molecular weight	H-bond acceptor / donor	XlogP	Lipinski's druglikeness
465582	CHEMBL3633665	C23H27N3O2	377.488	4 / 1	3.1	Yes
466306	CHEMBL3633653	C23H27N3O2	377.488	3 / 1	3.2	Yes
467590	CHEMBL3633651	C23H24FN3O3	409.461	5 / 1	2.7	Yes
468232	CHEMBL3633652	C17H21N3O3	315.373	4 / 1	1.3	Yes
469087	CHEMBL3633662	C22H23N3O3	377.444	4 / 2	2.2	Yes
472840	CHEMBL3633663	C26H29N3O3	431.536	4 / 1	3.0	Yes
473503	CHEMBL3633650	C23H25N3O3	391.471	4 / 1	2.6	Yes
476717	CHEMBL3633664	C23H25N3O2	375.472	3 / 1	3.5	Yes
480506	CHEMBL3633655	C23H24FN3O3	409.461	5 / 1	2.7	Yes
153855	calindol	C21H20N2	300.405	1 / 2	4.6	Yes
483168	CHEMBL3633659	C18H23N3O4	345.399	5 / 2	0.1	Yes
486971	CHEMBL3633656	C24H27N3O4	421.497	5 / 1	2.6	Yes
487395	CHEMBL3633658	C27H32N4O4	476.577	5 / 1	2.0	Yes
487585	CHEMBL3633654	C24H27N3O4	421.497	5 / 1	2.6	Yes
451077	L-arginine	C6H14N4O2	174.204	4 / 4	-4.2	Yes
495448	CHEMBL3633660	C23H27N3O3	393.487	4 / 2	2.1	Yes
554633	NPS-2143	C24H25ClN2O2	408.926	4 / 2	5.0	Yes
498003	CHEMBL3633661	C22H23N3O3	377.444	3 / 1	2.3	Yes
454229	CHEMBL3347674	C7H14N4O2	186.215	4 / 4	-4.3	Yes
454230	CHEMBL3347673	C7H14N4O2	186.215	4 / 4	-4.3	Yes
517126	CHEMBL3633657	C21H23N3O4	381.432	5 / 1	1.7	Yes