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BioLiP E. coli GLASS GPCR-HGmod GPCR-RD GPCR-EXP Tara-3D TM-fold DECOYS POTENTIAL RW/RWplus EvoEF HPSF THE-DB ADDRESS Alpaca-Antibody CASP7 CASP8 CASP9 CASP10 CASP11 CASP12 CASP13 CASP14

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GPCR

NameMuscarinic acetylcholine receptor M3
SpeciesMus musculus (Mouse)
GeneChrm3
Synonymcholinergic receptor, muscarinic 3
cholinergic receptor, muscarinic 3, cardiac
Chrm-3
cholinergic receptor
M3 receptor
[ Show all ]
DiseaseN/A for non-human GPCRs
Length589
Amino acid sequenceMTLHSNSTTSPLFPNISSSWVHSPSEAGLPLGTVSQLDSYNISQTSGNFSSNDTSSDPLGGHTIWQVVFIAFLTGFLALVTIIGNILVIVAFKVNKQLKTVNNYFLLSLACADLIIGVISMNLFTTYIIMNRWALGNLACDLWLSIDYVASNASVMNLLVISFDRYFSITRPLTYRAKRTTKRAGVMIGLAWVISFVLWAPAILFWQYFVGKRTVPPGECFIQFLSEPTITFGTAIAAFYMPVTIMTILYWRIYKETEKRTKELAGLQASGTEAEAENFVHPTGSSRSCSSYELQQQGTKRSSRRKYGGCHFWFTTKSWKPSAEQMDQDHSSSDSWNNNDAAASLENSASSDEEDIGSETRAIYSIVLKLPGHSTILNSTKLPSSDNLQVPDKDLGTMDVERNAHKLQAQKSMDDRDNCQKDFSKLPIQLESAVDTAKTSDTNSSVDKTTAALPLSFKEATLAKRFALKTRSQITKRKRMSLIKEKKAAQTLSAILLAFIITWTPYNIMVLVNTFCDSCIPKTYWNLGYWLCYINSTVNPVCYALCNKTFRTTFKMLLLCQCDKRKRRKQQYQQRQSVIFHKRVPEQAL
UniProtQ9ERZ3
Protein Data BankN/A
GPCR-HGmod modelN/A
3D structure modelNo available structures or models
BioLiPN/A
Therapeutic Target DatabaseN/A
ChEMBLCHEMBL5105
IUPHARN/A
DrugBankN/A

Known ligands

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Total entries: 52
Page:  / 1 

GLASS IDMoleculeFormulaMolecular weightH-bond acceptor / donorXlogPLipinski's druglikeness
66162D structurecarbacholC6H15ClN2O2182.6483 / 1N/AN/A
69142D structureCHEMBL1201912C16H24N2O7356.3758 / 2N/AN/A
130622D structure158142-45-1C6H10N2O2142.1583 / 1-0.9Yes
139372D structureCHEMBL1201901C15H24N2O6328.3657 / 3N/AN/A
257232D structure114724-56-0C9H13N3O179.2234 / 00.8Yes
277662D structureCHEMBL1201924C14H21FN2O5316.3297 / 2N/AN/A
277672D structureCHEMBL1201923C14H21FN2O5316.3297 / 2N/AN/A
307822D structureCHEMBL1201914C15H24N2O6328.3657 / 3N/AN/A
349352D structureCHEMBL1178347C8H12N4O2196.215 / 1-1.1Yes
360512D structureCHEMBL1201908C13H21N3O5299.3277 / 3N/AN/A
370312D structureCHEMBL538467C6H11ClN2O2178.6163 / 2N/AN/A
389842D structureCHEMBL1201907C12H18N2O5270.2856 / 2N/AN/A
522562D structureCHEMBL1183133C8H12N4OS212.2715 / 1-0.3Yes
597032D structureUNII-KU4UTQ0410C10H13F3N4O3294.2349 / 2N/AN/A
687632D structureCHEMBL1201919C17H26N2O7370.4028 / 2N/AN/A
707612D structureCHEMBL1201904C20H24N2O7404.4198 / 2N/AN/A
772032D structureCHEMBL1201900C15H24N2O6328.3657 / 3N/AN/A
995112D structureCHEMBL1201917C16H26N2O6342.3927 / 3N/AN/A
1099232D structureCHEMBL11095C13H20N2O3252.3144 / 1-2.4Yes
1164272D structurearecolineC8H13NO2155.1973 / 00.3Yes
1259472D structureOxotremorine 1C11H18N2O194.2782 / 00.3Yes
1386482D structureUNII-9F064NJ81DC8H12N4O180.2114 / 10.1Yes
1452662D structureCHEMBL1201903C17H26N2O7370.4028 / 2N/AN/A
1559872D structureXANOMELINEC14H23N3OS281.4185 / 03.3Yes
1564432D structureCHEMBL1201902C14H22N2O6314.3387 / 3N/AN/A
1618902D structure5-propargyloxycarbonyl-1,4,5,6-tetrahydropyrimidine hydrochlorideC8H11ClN2O2202.6383 / 2N/AN/A
1668902D structureZINC1535055C8H10N2O2166.183 / 1-0.8Yes
2089742D structureCID 44457650C10H13F3N4O4310.23310 / 2N/AN/A
2209732D structure158930-48-4C7H12N2O2156.1853 / 1-1.0Yes
2395442D structureCHEMBL1201921C13H20N2O6300.3117 / 3N/AN/A
2414112D structureCHEMBL1201925C14H22N2O6314.3387 / 3N/AN/A
2414122D structureCHEMBL1201910C14H22N2O6314.3387 / 3N/AN/A
2579302D structuremethyl 6-amino-2,3,4,5-tetrahydropyridine-3-carboxylate hydrochlorideC7H13ClN2O2192.6433 / 2N/AN/A
2701942D structureCHEMBL1201922C15H24N2O6328.3657 / 2N/AN/A
2728412D structureCHEMBL376781C23H24FN3OS2441.5835 / 14.0Yes
2806662D structureCHEMBL1201918C14H22N2O6314.3387 / 3N/AN/A
2808812D structureCID 44457579C10H13F3N4O3S326.29410 / 2N/AN/A
3037652D structureOxotremorineC12H18N2O206.2892 / 00.4Yes
3091262D structureCHEMBL1201916C17H26N2O7370.4028 / 2N/AN/A
3103932D structureSCHEMBL8305377C7H10N4O166.1844 / 1-0.4Yes
3119472D structureCHEMBL1201906C20H26N2O8S454.4949 / 2N/AN/A
3144332D structureCHEMBL541398C7H13ClN2O2192.6433 / 2N/AN/A
3269162D structureCHEMBL1201905C14H22N2O8S378.3969 / 2N/AN/A
3396072D structureCHEMBL557795C9H13ClN2O2216.6653 / 2N/AN/A
3441282D structureZINC3786169C7H12N2O2156.1853 / 1-0.5Yes
3493172D structureCHEMBL1201920C14H22N2O5298.3396 / 2N/AN/A
3568892D structureCHEMBL1201926C13H19FN2O5302.3027 / 2N/AN/A
3596382D structureSCHEMBL8307259C9H11F3N4O3280.2079 / 2N/AN/A
3609392D structureCarbamylcholineC6H15N2O2+147.1982 / 1-0.4Yes
3804682D structureaceclidineC9H15NO2169.2243 / 00.7Yes
3943082D structureCHEMBL557795C9H12N2O2180.2073 / 1-0.9Yes
4072202D structureCHEMBL1201913C15H23N3O6341.3647 / 2N/AN/A

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