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GPCR

NameAlpha-1A adrenergic receptor
SpeciesCavia porcellus (Guinea pig)
GeneADRA1A
SynonymAlpha-1A adrenoceptor
Alpha-1A adrenoreceptor
Alpha-1C adrenergic receptor
DiseaseN/A for non-human GPCRs
Length466
Amino acid sequenceMVFLSGNASDSSNCTQPPAPVNIPKAILLGVILGVLILFGVPGNILVILSVACHRHLHSVTHYYIVNLAVADLLLTSTVLPFSAIFEILGYWAFGRVFCNIWAAVDVLCCTASIMSLCIISIDRYIGVSYPLRYPTIVTQRRGLRALLCLWALSLVISIGPLFGWRQPAPQDETICQINEDPSYVLFSALGSFYVPLAIILVMYCRVYVVAKRESRGLTSGLKTDKSDSEQVTLRIHRKNAPLGGSGVASSKNKTHFSVRLLKFSREKKAAKTLGIVVGCFVLCWLPFFLVMPIGSFFPDFKPSETVFKIVFWLGYLNSCINPIIYPCSSQEFKKAFQNVLKIQCLRRKQSSKHALGYTLHPPSQAVEGQHKDMVRIPVGSRETFYKISKTDGVCEWKFFSSMPRGSARITVPKDQSACTTARVRSKSFLQVCCCVGPSTPNPGENHQVPTIKIHTISLSENGEEV
UniProtQ9WU25
Protein Data BankN/A
GPCR-HGmod modelN/A
3D structure modelNo available structures or models
BioLiPN/A
Therapeutic Target DatabaseN/A
ChEMBLCHEMBL2150843
IUPHARN/A
DrugBankN/A

Known ligands

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Total entries: 20
Page:  / 1 

GLASS IDMoleculeFormulaMolecular weightH-bond acceptor / donorXlogPLipinski's druglikeness
178842D structureBmy-7378C22H31N3O3385.5085 / 02.8Yes
617672D structureCID 10621591C20H26ClNO6411.8797 / 1N/AN/A
622412D structurespiperoneC23H26FN3O2395.4785 / 13.0Yes
1056782D structureCID 10834792C19H23ClFNO5399.8437 / 1N/AN/A
1157322D structure5-MethylurapidilC21H31N5O3401.5116 / 11.9Yes
1310312D structureCHEMBL2153551C19H24ClNO6397.8527 / 3N/AN/A
1313522D structureprazosinC19H21N5O4383.4088 / 12.0Yes
1643272D structureCHEMBL215421C19H24ClNO5381.8536 / 2N/AN/A
1717962D structurethioridazineC21H26N2S2370.5734 / 05.9No
2040252D structureNiguldipine(+)C36H39N3O6609.7238 / 06.2No
2914902D structurerisperidoneC23H27FN4O2410.4936 / 02.7Yes
2990312D structuremethiothepinC20H24N2S2356.5464 / 04.2Yes
3129782D structuredl-ArterenolC8H11NO3169.184 / 4-1.2Yes
3217832D structureCHEMBL2153555C19H23Cl2NO5416.2956 / 2N/AN/A
3241882D structureCID 10549595C20H26ClNO6411.8797 / 1N/AN/A
3337412D structureAC1NJ58PC9H13NO3183.2073 / 3-0.7Yes
3464572D structureSCHEMBL8097715C25H27NO5421.4936 / 14.4Yes
3758922D structureSkf 104856C14H14ClNS263.7832 / 04.2Yes
3857762D structureoxymetazolineC16H24N2O260.3812 / 22.9Yes
4340972D structurechlorpromazineC17H19ClN2S318.8633 / 05.2No

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