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Ligand

NameAF-353
Molecular formulaC14H17IN4O2
IUPAC name5-(5-iodo-4-methoxy-2-propan-2-ylphenoxy)pyrimidine-2,4-diamine
Molecular weight400.22
Hydrogen bond acceptor6
Hydrogen bond donor2
XlogP2.8
Synonyms5-(5-iodo-2-isopropyl-4-methoxy-phenoxy)-pyrimidine-2,4-diamine
A841708
HY-14483
5-(5-iodo-4-methoxy-2-propan-2-ylphenoxy)pyrimidine-2,4-diamine.
CTK2I3362
[ Show all ]
Inchi KeyAATPYXMXFBBKFO-UHFFFAOYSA-N
Inchi IDInChI=1S/C14H17IN4O2/c1-7(2)8-4-11(20-3)9(15)5-10(8)21-12-6-18-14(17)19-13(12)16/h4-7H,1-3H3,(H4,16,17,18,19)
PubChem CID15953802
ChEMBLCHEMBL526307
IUPHARN/A
BindingDB50257636
DrugBankN/A

Structure

SDF download

2D structure
Lipinski's druglikenessThis ligand satisfies Lipinski's rule of five.

Known GPCRs

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Total entries: 3
Page:  / 1 

GLASS IDNameUniProtGeneSpeciesLength
5315-hydroxytryptamine receptor 2AP28223HTR2AHomo sapiens (Human)471
5295-hydroxytryptamine receptor 6P50406HTR6Homo sapiens (Human)440
530Histamine H2 receptorP25021HRH2Homo sapiens (Human)359

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