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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL21607
Molecular formula	C28H27Cl2N3O2
IUPAC name	1-(4-benzyl-4-hydroxypiperidin-1-yl)-3-[6-chloro-2-(4-chlorophenyl)imidazo[1,2-a]pyridin-3-yl]propan-1-one
Molecular weight	508.443
Hydrogen bond acceptor	3
Hydrogen bond donor	1
XlogP	6.1
Synonyms	BDBM50099519 1-(4-Benzyl-4-hydroxy-piperidin-1-yl)-3-[6-chloro-2-(4-chloro-phenyl)-imidazo[1,2-a]pyridin-3-yl]-propan-1-one SCHEMBL7659714 1-(4-Hydroxy-4-benzylpiperidino)-3-[2-(4-chlorophenyl)-6-chloroimidazo[1,2-a]pyridine-3-yl]-1-propanone ABOQXCXLCHOJSM-UHFFFAOYSA-N 1-{3-[6-Chloro-2-(4-chlorophenyl)imidazo[1,2-a]pyridine-3-yl]-1-oxopropyl}-4-(phenylmethyl)-4-piperidinol [ Show all ]
Inchi Key	ABOQXCXLCHOJSM-UHFFFAOYSA-N
Inchi ID	InChI=1S/C28H27Cl2N3O2/c29-22-8-6-21(7-9-22)27-24(33-19-23(30)10-12-25(33)31-27)11-13-26(34)32-16-14-28(35,15-17-32)18-20-4-2-1-3-5-20/h1-10,12,19,35H,11,13-18H2
PubChem CID	10142159
ChEMBL	CHEMBL21607
IUPHAR	N/A
BindingDB	50099519
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons. This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
1038	Substance-P receptor	P25103	TACR1	Homo sapiens (Human)	407

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