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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL1394841
Molecular formula	C25H31N5O2
IUPAC name	(2,6-dimethyl-4-pyrrolidin-1-ylfuro[2,3-d]pyrimidin-5-yl)-[3-methyl-4-(3-methylphenyl)piperazin-1-yl]methanone
Molecular weight	433.556
Hydrogen bond acceptor	6
Hydrogen bond donor	0
XlogP	4.5
Synonyms	AKOS001951845 NCGC00126768-01 MCULE-7218923621 AKOS021692805 E948-0983 2,6-dimethyl-5-{[3-methyl-4-(3-methylphenyl)piperazin-1-yl]carbonyl}-4-pyrrolidin-1-ylfuro[2,3-d]pyrimidine MolPort-007-774-185 HMS1876D11 [ Show all ]
Inchi Key	ACRZMWYPAHJVAS-UHFFFAOYSA-N
Inchi ID	InChI=1S/C25H31N5O2/c1-16-8-7-9-20(14-16)30-13-12-29(15-17(30)2)25(31)21-18(3)32-24-22(21)23(26-19(4)27-24)28-10-5-6-11-28/h7-9,14,17H,5-6,10-13,15H2,1-4H3
PubChem CID	16023751
ChEMBL	CHEMBL1394841
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
463168	Parathyroid hormone/parathyroid hormone-related peptide receptor	Q03431	PTH1R	Homo sapiens (Human)	593

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