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Ligand

Namevalsartan
Molecular formulaC24H29N5O3
IUPAC name(2S)-3-methyl-2-[pentanoyl-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]amino]butanoic acid
Molecular weight435.528
Hydrogen bond acceptor6
Hydrogen bond donor2
XlogP4.4
SynonymsCGP-48933
(2S)-3-Methyl-2-{N-pentanoyl-N'-[2'-(1H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-amino}-butanoic acid
D06UDG
(S)-3-Methyl-2-{pentanoyl-[2''-(2H-tetrazol-5-yl)-biphenyl-4-ylmethyl]-amino}-butyric acid
Esteve brand of valsartan
[ Show all ]
Inchi KeyACWBQPMHZXGDFX-QFIPXVFZSA-N
Inchi IDInChI=1S/C24H29N5O3/c1-4-5-10-21(30)29(22(16(2)3)24(31)32)15-17-11-13-18(14-12-17)19-8-6-7-9-20(19)23-25-27-28-26-23/h6-9,11-14,16,22H,4-5,10,15H2,1-3H3,(H,31,32)(H,25,26,27,28)/t22-/m0/s1
PubChem CID60846
ChEMBLCHEMBL1069
IUPHAR3937, 593
BindingDB50049186
DrugBankDB00177

Structure

SDF download

2D structure
Lipinski's druglikenessThis ligand satisfies Lipinski's rule of five.

Known GPCRs

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Total entries: 3
Page:  / 1 

GLASS IDNameUniProtGeneSpeciesLength
1986Type-1 angiotensin II receptorP30556AGTR1Homo sapiens (Human)359
1988Type-1A angiotensin II receptorP25095Agtr1Rattus norvegicus (Rat)359
1987Type-1B angiotensin II receptorP29089Agtr1bRattus norvegicus (Rat)359

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