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Ligand

Namedonepezil
Molecular formulaC24H29NO3
IUPAC name2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimethoxy-2,3-dihydroinden-1-one
Molecular weight379.5
Hydrogen bond acceptor4
Hydrogen bond donor0
XlogP4.3
SynonymsCTK4C2920
Donepezil (INN)
1-Benzyl-4-[(5,6-dimethoxy-1-oxoindan-2-yl)methyl]piperidine; Donepezil
Eranz
2-[(1-benzyl-4-piperidyl)methyl]- 5,6-dimethoxy-2,3-dihydroinden-1-one
[ Show all ]
Inchi KeyADEBPBSSDYVVLD-UHFFFAOYSA-N
Inchi IDInChI=1S/C24H29NO3/c1-27-22-14-19-13-20(24(26)21(19)15-23(22)28-2)12-17-8-10-25(11-9-17)16-18-6-4-3-5-7-18/h3-7,14-15,17,20H,8-13,16H2,1-2H3
PubChem CID3152
ChEMBLCHEMBL502
IUPHARN/A
BindingDB8960
DrugBankDB00843

Structure

SDF download

2D structure
Lipinski's druglikenessThis ligand satisfies Lipinski's rule of five.

Known GPCRs

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Total entries: 2
Page:  / 1 

GLASS IDNameUniProtGeneSpeciesLength
21625-hydroxytryptamine receptor 2AP28223HTR2AHomo sapiens (Human)471
2161Histamine H3 receptorQ9Y5N1HRH3Homo sapiens (Human)445

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