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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	SMR000172981
Molecular formula	C31H31FN4O4S
IUPAC name	4-amino-N-[2-(cyclopentylamino)-1-(4-methoxyphenyl)-2-oxoethyl]-N-(4-fluorophenyl)-3-(4-methoxyphenyl)-1,2-thiazole-5-carboxamide
Molecular weight	574.671
Hydrogen bond acceptor	8
Hydrogen bond donor	2
XlogP	6.2
Synonyms	CHEMBL1459143 MLS000568670 4-amino-N-[2-(cyclopentylamino)-1-(4-methoxyphenyl)-2-oxoethyl]-N-(4-fluorophenyl)-3-(4-methoxyphenyl)-1,2-thiazole-5-carboxamide ASN 04936489 Oprea1_767444 HMS2417E09 MLS002536820 AC1MLCOF MCULE-9218145043 4-Amino-3-(4-methoxy-phenyl)-isothiazole-5-carboxylic acid [cyclopentylcarbamoyl-(4-methoxy-phenyl)-methyl]-(4-fluoro-phenyl)-amide AKOS000698026 Oprea1_358326 [ Show all ]
Inchi Key	ADYMMHMVAVEKAG-UHFFFAOYSA-N
Inchi ID	InChI=1S/C31H31FN4O4S/c1-39-24-15-7-19(8-16-24)27-26(33)29(41-35-27)31(38)36(23-13-11-21(32)12-14-23)28(20-9-17-25(40-2)18-10-20)30(37)34-22-5-3-4-6-22/h7-18,22,28H,3-6,33H2,1-2H3,(H,34,37)
PubChem CID	3192708
ChEMBL	CHEMBL1459143
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons. This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
3225	Glucagon-like peptide 1 receptor	P43220	GLP1R	Homo sapiens (Human)	463

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