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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL1084895
Molecular formula	C24H25F3N4O2
IUPAC name	N-[3-(2-methylpyrazol-3-yl)-4-(2-pyrrolidin-1-ylethoxy)phenyl]-4-(trifluoromethyl)benzamide
Molecular weight	458.485
Hydrogen bond acceptor	7
Hydrogen bond donor	1
XlogP	4.1
Synonyms	SCHEMBL1165616 N-[3-(2-methyl-2H-pyrazol-3-yl)-4-(2-pyrrolidin-1-yl-ethoxy)-phenyl]4-trifluoromethyl-benzamide ADZOFZRDWPGJCH-UHFFFAOYSA-N N-[3-(2-Methyl-2H-pyrazol-3-yl)-4-(2-pyrrolidin-1-ylethoxy)-phenyl]-4-trifluoromethyl-benzamide BDBM50319413 N-[3-(2-methyl-2H-pyrazol-3-yl)-4-(2-pyrrolidin-1-yl-ethoxy)-phenyl]-4-trifluoromethyl-benzamide [ Show all ]
Inchi Key	ADZOFZRDWPGJCH-UHFFFAOYSA-N
Inchi ID	InChI=1S/C24H25F3N4O2/c1-30-21(10-11-28-30)20-16-19(8-9-22(20)33-15-14-31-12-2-3-13-31)29-23(32)17-4-6-18(7-5-17)24(25,26)27/h4-11,16H,2-3,12-15H2,1H3,(H,29,32)
PubChem CID	11719524
ChEMBL	CHEMBL1084895
IUPHAR	N/A
BindingDB	50319413
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
3262	5-hydroxytryptamine receptor 2A	P28223	HTR2A	Homo sapiens (Human)	471
3263	5-hydroxytryptamine receptor 2C	P28335	HTR2C	Homo sapiens (Human)	458

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