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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	1-cyclohexyl-2-imino-3-[(4-methylphenyl)sulfonyl]-1,2-dihydro-5H-dipyrido[1,2-a:2',3'-d]pyrimidin-5-one
Molecular formula	C24H24N4O3S
IUPAC name	7-cyclohexyl-6-imino-5-(4-methylphenyl)sulfonyl-1,7,9-triazatricyclo[8.4.0.03,8]tetradeca-3(8),4,9,11,13-pentaen-2-one
Molecular weight	448.541
Hydrogen bond acceptor	5
Hydrogen bond donor	1
XlogP	3.2
Synonyms	CHEMBL1732193 ZINC6190412 1-cyclohexyl-2-imino-3-[(4-methylphenyl)sulfonyl]-1,2-dihydro-5H-dipyrido[1,2-a:2,3-d]pyrimidin-5-one MLS001124086 AKOS001654785 SMR000665684 HMS2972E18 606952-79-8 MolPort-000-186-585 STK814690 MCULE-1247867183 AC1LPHL5 MolPort-006-808-643 [ Show all ]
Inchi Key	AFEAXIZISCNBEA-UHFFFAOYSA-N
Inchi ID	InChI=1S/C24H24N4O3S/c1-16-10-12-18(13-11-16)32(30,31)20-15-19-23(26-21-9-5-6-14-27(21)24(19)29)28(22(20)25)17-7-3-2-4-8-17/h5-6,9-15,17,25H,2-4,7-8H2,1H3
PubChem CID	1307209
ChEMBL	CHEMBL1732193
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
441876	Glucagon-like peptide 1 receptor	P43220	GLP1R	Homo sapiens (Human)	463

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