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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	5-(4-fluorophenyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carboxylic acid
Molecular formula	C14H7F4N3O2
IUPAC name	5-(4-fluorophenyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidine-2-carboxylic acid
Molecular weight	325.223
Hydrogen bond acceptor	8
Hydrogen bond donor	1
XlogP	2.9
Synonyms	5-(4-fluorophenyl)-7-(trifluoromethyl)-8-hydropyrazolo[1,5-a]pyrimidine-2-carb oxylic acid CHEMBL1301751 SCHEMBL3284626 AC1LFOKO MCULE-6401034858 SR-01000596984-1 310451-82-2 CCG-202866 pyrazolo[1,5-a]pyrimidine-2-carboxylic acid, 5-(4-fluorophenyl)-7-(trifluoromethyl)- ZINC275873 5-(4-Fluorophenyl)-7-(trifluoromethyl)pyrazolo-[1,5-a]pyrimidine-2-carboxylic acid CTK7C0252 SMR000105288 AKOS000304183 MLS000109344 STK315607 5-(4-Fluoro-phenyl)-7-trifluoromethyl-pyrazolo[1,5-a]pyrimidine-2-carboxylic acid SBB019787 HMS2276J14 SR-01000596984 ALBB-009968 MolPort-000-162-985 TR-061506 [ Show all ]
Inchi Key	AFSLRXYYANFMSX-UHFFFAOYSA-N
Inchi ID	InChI=1S/C14H7F4N3O2/c15-8-3-1-7(2-4-8)9-5-11(14(16,17)18)21-12(19-9)6-10(20-21)13(22)23/h1-6H,(H,22,23)
PubChem CID	781426
ChEMBL	CHEMBL1301751
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
463427	Parathyroid hormone/parathyroid hormone-related peptide receptor	Q03431	PTH1R	Homo sapiens (Human)	593

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