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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	AC1MHCQD
Molecular formula	C25H24N2O5
IUPAC name	4-hydroxy-3-(5-methylfuran-2-carbonyl)-2-(4-propoxyphenyl)-1-(pyridin-3-ylmethyl)-2H-pyrrol-5-one
Molecular weight	432.476
Hydrogen bond acceptor	6
Hydrogen bond donor	1
XlogP	4.1
Synonyms	638134-03-9 NCGC00056778-02 AKOS016297389 HMS2350C04 ST50074514 3-hydroxy-4-[(5-methyl(2-furyl))carbonyl]-5-(4-propoxyphenyl)-1-(3-pyridylmeth yl)-3-pyrrolin-2-one MolPort-000-452-758 AKOS002182863 CHEMBL1323117 [ Show all ]
Inchi Key	AGCULGAKHCAUSH-UHFFFAOYSA-N
Inchi ID	InChI=1S/C25H24N2O5/c1-3-13-31-19-9-7-18(8-10-19)22-21(23(28)20-11-6-16(2)32-20)24(29)25(30)27(22)15-17-5-4-12-26-14-17/h4-12,14,22,29H,3,13,15H2,1-2H3
PubChem CID	2949891
ChEMBL	CHEMBL1323117
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
463467	fMet-Leu-Phe receptor	P21462	FPR1	Homo sapiens (Human)	350
4776	Neuropeptide S receptor	Q6W5P4	NPSR1	Homo sapiens (Human)	371

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