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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	SMR000261664
Molecular formula	C22H18Cl2F2N4S2
IUPAC name	1-(4-chloro-3-fluorophenyl)-3-[[4-[[(4-chloro-3-fluorophenyl)carbamothioylamino]methyl]phenyl]methyl]thiourea
Molecular weight	511.431
Hydrogen bond acceptor	4
Hydrogen bond donor	4
XlogP	5.6
Synonyms	CHEBI:105872 HMS2763G11 AC1M7M9P MLS001332811 ZINC13865602 MCULE-7072275042 AKOS008028778 MolPort-005-888-244 CHEMBL1507504 1-(4-chloro-3-fluorophenyl)-3-[[4-[[(4-chloro-3-fluorophenyl)carbamothioylamino]methyl]phenyl]methyl]thiourea MLS000392678 [ Show all ]
Inchi Key	AGOYBDGDMVYPKN-UHFFFAOYSA-N
Inchi ID	InChI=1S/C22H18Cl2F2N4S2/c23-17-7-5-15(9-19(17)25)29-21(31)27-11-13-1-2-14(4-3-13)12-28-22(32)30-16-6-8-18(24)20(26)10-16/h1-10H,11-12H2,(H2,27,29,31)(H2,28,30,32)
PubChem CID	2421054
ChEMBL	CHEMBL1507504
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand is heavier than 500 daltons. This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
5090	Glucagon-like peptide 1 receptor	P43220	GLP1R	Homo sapiens (Human)	463
463496	Parathyroid hormone/parathyroid hormone-related peptide receptor	Q03431	PTH1R	Homo sapiens (Human)	593

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