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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL1357595
Molecular formula	C24H17ClFN3O
IUPAC name	3-(4-chlorophenyl)-4-(4-fluorophenyl)-5-(4-methylphenyl)-1,4-dihydropyrrolo[3,4-c]pyrazol-6-one
Molecular weight	417.868
Hydrogen bond acceptor	3
Hydrogen bond donor	1
XlogP	5.6
Synonyms	C390-0262 HMS1824K13 AKOS001791771 NCGC00108491-01 MCULE-6840684075 AKOS022042409 3-(4-chlorophenyl)-4-(4-fluorophenyl)-5-(4-methylphenyl)-4,5-dihydropyrrolo[3,4-c]pyrazol-6(1H)-one MolPort-007-628-297 [ Show all ]
Inchi Key	AHKDUTFBJXLQEI-UHFFFAOYSA-N
Inchi ID	InChI=1S/C24H17ClFN3O/c1-14-2-12-19(13-3-14)29-23(16-6-10-18(26)11-7-16)20-21(27-28-22(20)24(29)30)15-4-8-17(25)9-5-15/h2-13,23H,1H3,(H,27,28)
PubChem CID	16020071
ChEMBL	CHEMBL1357595
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand has a partition coefficient log P greater than 5.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
5645	Glucagon-like peptide 1 receptor	P43220	GLP1R	Homo sapiens (Human)	463

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