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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	1-[4-(4-benzylpiperazin-1-yl)-6-methyl-1-phenyl-2-thioxo-1,2-dihydropyrimidin-5-yl]ethanone
Molecular formula	C24H26N4OS
IUPAC name	1-[4-(4-benzylpiperazin-1-yl)-6-methyl-1-phenyl-2-sulfanylidenepyrimidin-5-yl]ethanone
Molecular weight	418.559
Hydrogen bond acceptor	3
Hydrogen bond donor	0
XlogP	3.2
Synonyms	AKOS001681389 STK325061 HMS2676L05 AB00098154-01 MolPort-003-002-927 ZINC55450408 1-[4-(4-benzylpiperazin-1-yl)-6-methyl-1-phenyl-2-sulfanylidenepyrimidin-5-yl]ethanone MCULE-6849074256 AC1NPSE8 SMR000306466 CHEMBL1328236 MLS000727769 [ Show all ]
Inchi Key	AHMLOLDNWKPJLS-UHFFFAOYSA-N
Inchi ID	InChI=1S/C24H26N4OS/c1-18-22(19(2)29)23(25-24(30)28(18)21-11-7-4-8-12-21)27-15-13-26(14-16-27)17-20-9-5-3-6-10-20/h3-12H,13-17H2,1-2H3
PubChem CID	5184323
ChEMBL	CHEMBL1328236
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
463568	Parathyroid hormone/parathyroid hormone-related peptide receptor	Q03431	PTH1R	Homo sapiens (Human)	593

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