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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	MLS000557918
Molecular formula	C20H24N4O2
IUPAC name	N-[7-methyl-1-(2-methylpropyl)pyrazolo[3,4-b]quinolin-3-yl]oxolane-2-carboxamide
Molecular weight	352.438
Hydrogen bond acceptor	4
Hydrogen bond donor	1
XlogP	3.7
Synonyms	N-(1-isobutyl-7-methyl-pyrazolo[3,4-b]quinolin-3-yl)tetrahydrofuran-2-carboxamide N-[7-methyl-1-(2-methylpropyl)pyrazolo[3,4-b]quinolin-3-yl]oxolane-2-carboxamide AC1N64WO HMS2410N04 Tetrahydro-furan-2-carboxylic acid (1-isobutyl-7-methyl-1H-pyrazolo[3,4-b]quinolin-3-yl)-amide BDBM68792 MolPort-000-756-411 N-[(3E)-7-methyl-1-(2-methylpropyl)-1,2-dihydro-3H-pyrazolo[3,4-b]quinolin-3-ylidene]tetrahydrofuran-2-carboxamide CHEMBL1302024 SMR000148634 AKOS005495000 MCULE-8173820049 BRD-A75867812-001-08-0 MolPort-002-623-999 N-[7-methyl-1-(2-methylpropyl)-3-pyrazolo[3,4-b]quinolinyl]-2-oxolanecarboxamide 713089-04-4 cid_4209814 STK569603 AKOS032390502 [ Show all ]
Inchi Key	AHTCKTSEEJTFQI-UHFFFAOYSA-N
Inchi ID	InChI=1S/C20H24N4O2/c1-12(2)11-24-19-15(10-14-7-6-13(3)9-16(14)21-19)18(23-24)22-20(25)17-5-4-8-26-17/h6-7,9-10,12,17H,4-5,8,11H2,1-3H3,(H,22,23,25)
PubChem CID	4209814
ChEMBL	CHEMBL1302024
IUPHAR	N/A
BindingDB	N/A
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
5864	Thyrotropin-releasing hormone receptor	P34981	TRHR	Homo sapiens (Human)	398

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