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Ligand

NameSCHEMBL4536325
Molecular formulaC20H18ClF4NO3
IUPAC name(3S,5S)-5-(2-chloro-6-ethoxyphenyl)-3-fluoro-1-[[4-(trifluoromethoxy)phenyl]methyl]pyrrolidin-2-one
Molecular weight431.812
Hydrogen bond acceptor7
Hydrogen bond donor0
XlogP5.4
SynonymsUS9242970, 436
CHEMBL3919179
BDBM203253
Inchi KeyAIMZGLHDJDQGPJ-HOTGVXAUSA-N
Inchi IDInChI=1S/C20H18ClF4NO3/c1-2-28-17-5-3-4-14(21)18(17)16-10-15(22)19(27)26(16)11-12-6-8-13(9-7-12)29-20(23,24)25/h3-9,15-16H,2,10-11H2,1H3/t15-,16-/m0/s1
PubChem CID69082542
ChEMBLCHEMBL3919179
IUPHARN/A
BindingDB203253
DrugBankN/A

Structure

SDF download

2D structure
Lipinski's druglikenessThis ligand has a partition coefficient log P greater than 5.

Known GPCRs

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Total entries: 2
Page:  / 1 

GLASS IDNameUniProtGeneSpeciesLength
517352Orexin receptor type 1O43613HCRTR1Homo sapiens (Human)425
517351Orexin receptor type 2O43614HCRTR2Homo sapiens (Human)444

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