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Ligand

NameCHEMBL69968
Molecular formulaC18H19Cl2N5
IUPAC nameN-cyclopentyl-3-(2,4-dichlorophenyl)-2,5-dimethylpyrazolo[4,3-d]pyrimidin-7-amine
Molecular weight376.285
Hydrogen bond acceptor4
Hydrogen bond donor1
XlogP4.8
SynonymsN-Cyclopentyl-2,5-dimethyl-3-(2,4-dichlorophenyl)-2H-pyrazolo[4,3-d]pyrimidine-7-amine
BDBM50116121
Cyclopentyl-[3-(2,4-dichloro-phenyl)-2,5-dimethyl-2H-pyrazolo[4,3-d]pyrimidin-7-yl]-amine
Inchi KeyAIVYXSGNYNBFLN-UHFFFAOYSA-N
Inchi IDInChI=1S/C18H19Cl2N5/c1-10-21-15-16(18(22-10)23-12-5-3-4-6-12)24-25(2)17(15)13-8-7-11(19)9-14(13)20/h7-9,12H,3-6H2,1-2H3,(H,21,22,23)
PubChem CID44308187
ChEMBLCHEMBL69968
IUPHARN/A
BindingDB50116121
DrugBankN/A

Structure

SDF download

2D structure
Lipinski's druglikenessThis ligand satisfies Lipinski's rule of five.

Known GPCRs

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Total entries: 1
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GLASS IDNameUniProtGeneSpeciesLength
6575Corticotropin-releasing factor receptor 1P34998CRHR1Homo sapiens (Human)444

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