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GLASS

You can:

Check the ligand table for details.
Go to the GPCR list to see GPCRs with which this ligand interacts.
Go to the individual GPCR page for PubMed ID information by text mining.
Download a TSV version of all interaction data.
Go back to previous page.

Ligand

Name	CHEMBL577831
Molecular formula	C17H21ClN4O
IUPAC name	2-[2-(3-chlorophenyl)ethyl]-3-methyl-6-piperazin-1-ylpyrimidin-4-one
Molecular weight	332.832
Hydrogen bond acceptor	4
Hydrogen bond donor	1
XlogP	1.7
Synonyms	BDBM50301782 2-(3-chlorophenethyl)-3-methyl-6-(piperazin-1-yl)pyrimidin-4(3H)-one
Inchi Key	AJDBFLVHURZULN-UHFFFAOYSA-N
Inchi ID	InChI=1S/C17H21ClN4O/c1-21-15(6-5-13-3-2-4-14(18)11-13)20-16(12-17(21)23)22-9-7-19-8-10-22/h2-4,11-12,19H,5-10H2,1H3
PubChem CID	45484886
ChEMBL	CHEMBL577831
IUPHAR	N/A
BindingDB	50301782
DrugBank	N/A
Structure SDF download
Lipinski's druglikeness	This ligand satisfies Lipinski's rule of five.

Known GPCRs

You can:

Click GLASS IDs to check the association information.
Click protein names to check details of the GPCRs.
Download a TSV version of all interaction information.

GLASS ID	Name	UniProt	Gene	Species	Length
6801	5-hydroxytryptamine receptor 2A	P28223	HTR2A	Homo sapiens (Human)	471
6800	5-hydroxytryptamine receptor 2B	P41595	HTR2B	Homo sapiens (Human)	481
6802	5-hydroxytryptamine receptor 2C	P28335	HTR2C	Homo sapiens (Human)	458

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